SCHEMBL26467679

SCHEMBL26467679

CC(=O)c1nnn(Cc2ccc(C)cc2)c1Oc1ccc(Br)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.45
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
POLB P06746 2/20 0.40
TSHR P16473 1/20 0.40
PFKFB3 Q16875 2/20 0.39
ALOX15 P16050 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KDM4E B2RXH2 1/20 0.39
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
HSD17B10 Q99714 1/20 0.39
NPBWR1 P48145 1/20 0.39
MCHR1 Q99705 1/20 0.39
NAMPT P43490 1/20 0.39
MAPT P10636 2/20 0.38
MAOB P27338 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26467692 0.94 CYP19A1 (0.46) CYP19A1MEN1KMT2APOLBTSHR
SCHEMBL26467846 0.91 ALOX15 (0.49) CYP19A1MEN1KMT2APOLBALOX15
SCHEMBL26467790 0.89 SMN1; SMN2 (0.47) CYP19A1MEN1KMT2APOLBTSHR
SCHEMBL21296928 0.81 ALOX15 (0.49) CYP19A1MEN1KMT2APOLBALOX15
SCHEMBL26467707 0.81 UCHL1 (0.42) CYP19A1MEN1KMT2APOLBTSHR
SCHEMBL25463546 0.81 ALOX15 (0.51) CYP19A1MEN1KMT2APOLBALOX15
SCHEMBL21296900 0.80 CYP19A1 (0.57) CYP19A1MEN1KMT2APOLBALOX15
SCHEMBL26467681 0.78 CYP19A1 (0.39) CYP19A1MEN1KMT2APOLBTSHR
SCHEMBL25464806 0.73 KCNH2 (0.49) MEN1KMT2APOLBALOX15L3MBTL1
SCHEMBL22815764 0.73 ALOX15 (0.45) CYP19A1MEN1KMT2APOLBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230129160-A1 PROCESSES FOR PREPARING TRIAZOLE GLYCOLATE OXIDASE INHIBITORS PHOENIX TISSUE REPAIR, INC. 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230129160-A1 PROCESSES FOR PREPARING TRIAZOLE GLYCOLATE OXIDASE INHIBITORS TH, AOX1, AOC3 CYP19A1 247/4885MEN1 4709/4885KMT2A 3703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.