SCHEMBL26467681

SCHEMBL26467681

CC(=O)c1nnn(Cc2ccc(C)cc2)c1Oc1ccc(-c2ccc(C3CC(F)(F)C3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.39
POLB P06746 2/20 0.36
MGLL Q99685 2/20 0.35
MAPT P10636 1/20 0.34
S1PR1 P21453 3/20 0.34
S1PR5 Q9H228 3/20 0.34
MCHR1 Q99705 2/20 0.34
TSHR P16473 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TRPV1 Q8NER1 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ALOX15 P16050 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
S1PR4 O95977 2/20 0.33
S1PR3 Q99500 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26467810 0.91 CYP19A1 (0.39) CYP19A1POLBMAPTMCHR1TSHR
SCHEMBL23319971 0.85 ALOX15 (0.42) POLBMAPTMEN1KMT2AKDM4E
SCHEMBL25463564 0.84 KDM4E (0.45) CYP19A1POLBMAPTMEN1KMT2A
SCHEMBL26467692 0.83 CYP19A1 (0.46) CYP19A1POLBMAPTMCHR1TSHR
SCHEMBL22816596 0.82 ALOX15 (0.42) POLBMAPTMEN1KMT2AKDM4E
SCHEMBL25465647 0.80 ALOX15 (0.41) POLBMAPTMCHR1HRH3MEN1
SCHEMBL25465650 0.79 KDM4E (0.43) CYP19A1POLBMAPTMEN1KMT2A
SCHEMBL26088232 0.78 S1PR4 (0.40) POLBMAPTS1PR1S1PR5MEN1
SCHEMBL26467679 0.78 CYP19A1 (0.45) CYP19A1POLBMAPTMCHR1TSHR
SCHEMBL26086645 0.76 ALOX15 (0.41) POLBMAPTMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230129160-A1 PROCESSES FOR PREPARING TRIAZOLE GLYCOLATE OXIDASE INHIBITORS PHOENIX TISSUE REPAIR, INC. 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230129160-A1 PROCESSES FOR PREPARING TRIAZOLE GLYCOLATE OXIDASE INHIBITORS TH, AOX1, AOC3 CYP19A1 247/4885POLB 1036/4885MGLL 436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.