Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.38 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PDE8B | O95263 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22816618 | 0.91 | CNR2 (0.42) | ALOX15L3MBTL1MEN1KMT2AAKR1C3 | |
| SCHEMBL23319971 | 0.89 | ALOX15 (0.42) | ALOX15L3MBTL1MEN1KMT2AAKR1C3 | |
| SCHEMBL25463564 | 0.87 | KDM4E (0.45) | ALOX15L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL22816848 | 0.85 | ALOX15 (0.42) | ALOX15L3MBTL1MEN1KMT2AAKR1C3 | |
| SCHEMBL26467810 | 0.83 | CYP19A1 (0.39) | ALOX15L3MBTL1MEN1KMT2AAKR1C3 | |
| SCHEMBL26088232 | 0.82 | S1PR4 (0.40) | ALOX15L3MBTL1MEN1KMT2AAKR1C3 | |
| SCHEMBL26467681 | 0.82 | CYP19A1 (0.39) | ALOX15L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL25465647 | 0.82 | ALOX15 (0.41) | ALOX15L3MBTL1MEN1KMT2AAKR1C3 | |
| SCHEMBL22816026 | 0.82 | ALDH1A1 (0.45) | ALOX15L3MBTL1MEN1KMT2AAKR1C3 | |
| SCHEMBL21296920 | 0.81 | NPBWR1 (0.51) | ALOX15L3MBTL1MEN1KMT2AAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |