Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13154972 | 0.83 | ALDH1A1 (0.45) | SLC6A4SLC6A2SLC6A3GABRA1GABRB2 | |
| SCHEMBL10121263 | 0.80 | GABRA1 (0.38) | SLC6A4SLC6A2SLC6A3HTR2AGABRA1 | |
| SCHEMBL26791146 | 0.79 | GABRA1 (0.37) | SLC6A4SLC6A2SLC6A3GABRA1GABRB2 | |
| SCHEMBL21649568 | 0.78 | PNMT (0.44) | PNMTSIGMAR1 | |
| SCHEMBL19135765 | 0.76 | SIGMAR1 (0.44) | SLC6A4SLC6A2SLC6A3ADRA2BADRA2C | |
| SCHEMBL8539519 | 0.76 | GABRA1 (0.50) | SLC6A4SLC6A2SLC6A3HTR2AGABRA1 | |
| SCHEMBL24300623 | 0.75 | PNMT (0.38) | SLC6A4SLC6A2SLC6A3HTR2AGABRA1 | |
| SCHEMBL11210488 | 0.75 | CRHBP (0.44) | HTR2ASIGMAR1 | |
| SCHEMBL18970416 | 0.75 | CRHBP (0.41) | SIGMAR1 | |
| SCHEMBL22388180 | 0.74 | IGLV6-57 (0.38) | GABRA1GABRB2PNMTSIGMAR1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4257587-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shenzhen Chipscreen Biosciences Co., Ltd. (CN) | 2023-10-11 | — | — | EP | disclosed |