SCHEMBL2651969

SCHEMBL2651969

c1ccc2nc(-c3ncc[nH]3)ccc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.59
RAB9A P51151 8/20 0.59
NPC1 O15118 7/20 0.59
KDM4E B2RXH2 7/20 0.59
HSD17B10 Q99714 4/20 0.59
PKM P14618 4/20 0.59
HPGD P15428 4/20 0.59
SMN1; SMN2 Q16637 4/20 0.59
TP53 P04637 3/20 0.59
ALOX15 P16050 2/20 0.59
TSHR P16473 1/20 0.59
AR P10275 5/20 0.50
CYP3A4 P08684 3/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2D6 P10635 2/20 0.50
NISCH Q9Y2I1 2/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
MTOR P42345 1/20 0.50
ADK P55263 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31241273 0.93 RAB9A (0.53) ALDH1A1RAB9ANPC1KDM4EHSD17B10
SCHEMBL28946289 0.80 ADORA3 (0.60) ALDH1A1RAB9ANPC1KDM4EHSD17B10
SCHEMBL197279 0.78 NISCH (0.54) ALDH1A1KDM4ESMN1; SMN2TP53ALOX15
SCHEMBL12075533 0.77 CCR1 (0.53) ALDH1A1KDM4ESMN1; SMN2TP53ALOX15
SCHEMBL14919456 0.76 RAB9A (0.53) ALDH1A1RAB9ANPC1KDM4EHSD17B10
Hydrochloric Acid SCHEMBL10653147 0.75 RAB9A (0.65) ALDH1A1RAB9ANPC1KDM4EHSD17B10
Hydrochloric Acid SCHEMBL2415958 0.75 RAB9A (0.65) ALDH1A1RAB9ANPC1KDM4EHSD17B10
SCHEMBL7125744 0.75 RAB9A (0.44) ALDH1A1RAB9ANPC1KDM4EHSD17B10
SCHEMBL8345707 0.75 METAP2 (0.47) ALDH1A1RAB9ANPC1KDM4EHSD17B10
SCHEMBL29374931 0.75 RAB9A (0.64) ALDH1A1RAB9ANPC1KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119684261-A Quinolinyl imidazoles Pb2+Preparation method and application of fluorescent probe 南京林业大学 2025-03-25 CN claimed
US-20250082652-A1 SIGNALLING-PATHWAY INHIBITOR COMBINATIONS FOR USE IN THE TREATMENT OF CANCER DISEASES UNIVERSITÄT ZU KÖLN (DE) 2025-03-13 US claimed
EP-4460301-A1 SIGNALLING-PATHWAY INHIBITOR COMBINATIONS FOR USE IN THE TREATMENT OF CANCER DISEASES Universität zu Köln (DE) 2024-11-13 EP claimed
CN-118745167-A Preparation method and application of quinolinyl imidazole boron trifluoride fluorescent probe 南京林业大学 2024-10-08 CN claimed
EP-3720493-B1 COMBINATIONS OF RIPK1- AND IKK-INHIBITORS FOR THE PREVENTION OR TREATMENT OF IMMUNE DISEASES UNIV KOELN (DE) 2024-07-24 EP claimed
WO-2023131576-A1 SIGNALLING-PATHWAY INHIBITOR COMBINATIONS FOR USE IN THE TREATMENT OF CANCER DISEASES UNIVERSITÄT ZU KÖLN (DE) 2023-07-13 WO claimed
EP-4209213-A1 SIGNALLING-PATHWAY INHIBITOR COMBINATIONS FOR USE IN THE TREATMENT OF CANCER DISEASES Universität zu Köln (DE) 2023-07-12 EP claimed
CN-112174962-A Synthesis method of benzo [ e ] pyridylimidazo [4,5-g ] isoindole-1, 3(2H) -diketone compound 河南师范大学 2021-01-05 CN claimed
CN-119684261-B Quinolinyl imidazoles Pb2+Preparation method and application of fluorescent probe 南京林业大学 2025-10-28 CN disclosed
CN-118745167-B Preparation method and application of quinolinyl imidazole boron trifluoride fluorescent probe 南京林业大学 2025-10-28 CN disclosed
CN-120058749-A OLED light-emitting layer guest material based on D-A type nitrogen-containing heterocyclic gallium compound and application thereof 北京师范大学 2025-05-30 CN disclosed
CN-116473077-B Synthesis and application of N, N coordinated gallium complex antibacterial agent 广东方中高新材料有限公司 2025-04-11 CN disclosed
CN-119684261-A Quinolinyl imidazoles Pb2+Preparation method and application of fluorescent probe 南京林业大学 2025-03-25 CN disclosed
CN-119684261-A Quinolinyl imidazoles Pb2+Preparation method and application of fluorescent probe 南京林业大学 2025-03-25 CN disclosed
EP-1534074-A2 COMBINATION THERAPY FOR THE TREATMENT OF OBESITY Merck & Co., Inc. (US) 2005-06-01 EP disclosed
WO-2005000217-A2 COMBINATION THERAPY FOR THE TREATMENT OF DYSLIPIDEMIA MERCK & CO., INC. (US) 2005-01-06 WO disclosed
WO-2004110375-A2 COMBINATION THERAPY FOR THE TREATMENT OF DIABETES MERCK & CO., INC. (US) 2004-12-23 WO disclosed
WO-2004110368-A2 COMBINATION THERAPY FOR THE TREATMENT OF HYPERTENSION MERCK & CO., INC. (US) 2004-12-23 WO disclosed
WO-2004009015-A2 COMBINATION THERAPY FOR THE TREATMENT OF OBESITY MERCK & CO., INC. (US) 2004-01-29 WO disclosed
CN-88102448-A NOVEL NITROGENOUS COMPOUND 1988-11-16 CN disclosed