SCHEMBL26528665

SCHEMBL26528665

Cc1cc(C)cc(-c2ccc3c(c2)c2cc(-c4cc(C)cc(C)c4)ccc2n3-c2ccccc2-c2ccc(C(F)(F)F)cc2)c1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.35
KIF11 P52732 2/20 0.35
MAPT P10636 4/20 0.34
BACE1 P56817 1/20 0.34
ICMT O60725 2/20 0.33
PPARG P37231 1/20 0.33
TP53 P04637 2/20 0.33
KDM1A O60341 1/20 0.33
PIK3CA P42336 1/20 0.32
TRPV1 Q8NER1 1/20 0.32
GLO1 Q04760 1/20 0.32
MAOB P27338 1/20 0.32
CHRM5 P08912 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.32
PDE2A O00408 1/20 0.32
PDE10A Q9Y233 1/20 0.32
TACR1 P25103 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26529015 0.90 ICMT (0.36) KIF11BACE1ICMTTACR1
SCHEMBL26529632 0.90 ICMT (0.36) ICMT
SCHEMBL26528662 0.90 SERPINE1 (0.38) AKT1MAPTPPARG
SCHEMBL26529003 0.89 ICMT (0.36) KIF11BACE1ICMTGLO1TACR1
SCHEMBL26529348 0.89 ICMT (0.36) ICMT
SCHEMBL26529265 0.89 KIF11 (0.42) AKT1KIF11MAPTBACE1ICMT
SCHEMBL26528984 0.89 ICMT (0.37) ICMT
SCHEMBL26537551 0.87 KIF11 (0.47) AKT1KIF11MAPTBACE1ICMT
SCHEMBL26528853 0.87 ICMT (0.34) ICMT
SCHEMBL26528643 0.87 MGLL (0.35) AKT1MAPTICMTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 AKT1 4255/4885KIF11 3651/4885MAPT 742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.