SCHEMBL26529265

SCHEMBL26529265

Cc1ccc(-c2cc(-c3ccc(C(F)(F)F)cc3)cc(-c3ccc4c(c3)c3cc(-c5cc(-c6ccc(C)cc6)cc(-c6ccc(C(F)(F)F)cc6)c5)ccc3n4-c3ccccc3-c3ccccc3)c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.42
BACE1 P56817 1/20 0.38
GLO1 Q04760 1/20 0.38
PTPN5 P54829 1/20 0.36
DHODH Q02127 2/20 0.36
PDK2 Q15119 1/20 0.36
ICMT O60725 1/20 0.36
MAPT P10636 4/20 0.35
ALDH1A1 P00352 2/20 0.35
KDM1A O60341 1/20 0.35
HPRT1 P00492 1/20 0.35
NPC1 O15118 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34
RAB9A P51151 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
AKT1 P31749 1/20 0.34
TOP1 P11387 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26537551 0.94 KIF11 (0.47) KIF11BACE1GLO1DHODHICMT
SCHEMBL26529346 0.92 ICMT (0.36) KIF11PTPN5PDK2ICMTMAPT
SCHEMBL26529256 0.90 HPRT1 (0.41) DHODHPDK2MAPTALDH1A1HPRT1
SCHEMBL26529441 0.90 ICMT (0.37) KIF11GLO1PTPN5PDK2ICMT
SCHEMBL26528665 0.89 AKT1 (0.35) KIF11BACE1GLO1ICMTMAPT
SCHEMBL26529297 0.89 TRPA1 (0.37) KIF11PTPN5PDK2ICMTALDH1A1
SCHEMBL26529003 0.88 ICMT (0.36) KIF11BACE1GLO1PTPN5DHODH
SCHEMBL26529015 0.87 ICMT (0.36) KIF11BACE1PDK2ICMT
SCHEMBL26537554 0.87 ICMT (0.41) KIF11ICMT
SCHEMBL26534128 0.87 ICMT (0.41) KIF11GLO1ICMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 KIF11 3651/4885BACE1 495/4885GLO1 949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.