SCHEMBL26528829

SCHEMBL26528829

CCc1ccccc1-n1c2ccc(-c3cc(C)cc(C(F)(F)F)c3)cc2c2cc(-c3cc(C)cc(C(F)(F)F)c3)ccc21

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ICMT O60725 12/20 0.41
RXRA P19793 3/20 0.38
RXRB P28702 3/20 0.38
RXRG P48443 1/20 0.38
NOTUM Q6P988 1/20 0.33
RORA P35398 1/20 0.33
NR2E1 Q9Y466 1/20 0.33
PTPN5 P54829 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26532285 0.93 ICMT (0.46) ICMTRXRARXRBRXRGPTPN5
SCHEMBL26528614 0.87 ALDH1A1 (0.36) ICMT
SCHEMBL26528827 0.86 RXRA (0.37) ICMTRXRARXRBRXRGNOTUM
SCHEMBL26528984 0.84 ICMT (0.37) ICMTRXRARXRBRXRGNOTUM
SCHEMBL26529085 0.83 RXRA (0.38) ICMTRXRARXRBRXRGNOTUM
SCHEMBL26529015 0.83 ICMT (0.36) ICMTRXRARXRBRXRG
SCHEMBL26529563 0.83 GAA (0.36) ICMTRXRARXRBRXRG
SCHEMBL26528887 0.83 KIF11 (0.37) ICMTRXRARXRBRXRGNOTUM
SCHEMBL26528830 0.83 ICMT (0.37) ICMTRXRARXRBRXRGNOTUM
SCHEMBL26528740 0.82 RXRB (0.41) ICMTRXRARXRBRXRGRORA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 ICMT 36/4885RXRA 1633/4885RXRB 2498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.