Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ME2 | P23368 | 1/20 | 0.54 |
| ▸ | ME1 | P48163 | 1/20 | 0.54 |
| ▸ | ME3 | Q16798 | 1/20 | 0.54 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | F12 | P00748 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4081943 | 0.83 | XDH (0.55) | L3MBTL1LMNAGPR35HTTADCY6 | |
| SCHEMBL4085751 | 0.82 | L3MBTL1 (0.61) | L3MBTL1LMNAME2ME1ME3 | |
| SCHEMBL2659032 | 0.81 | LMNA (0.53) | L3MBTL1LMNAME2ME1ME3 | |
| SCHEMBL4085756 | 0.78 | L3MBTL1 (0.56) | L3MBTL1LMNAME2ME1ME3 | |
| SCHEMBL21715531 | 0.78 | ME2 (0.53) | L3MBTL1ME2ME1ME3APEX1 | |
| SCHEMBL13800053 | 0.77 | LMNA (0.50) | LMNAGCGR | |
| SCHEMBL4096741 | 0.76 | ADCY6 (0.62) | GPR35KMT2AMEN1ADCY6ADCY3 | |
| SCHEMBL10575449 | 0.76 | F2 (0.56) | L3MBTL1F2ADORA1F12ADORA3 | |
| SCHEMBL2663409 | 0.75 | LMNA (0.48) | LMNAGCGR | |
| SCHEMBL3299661 | 0.75 | ADORA1 (0.70) | L3MBTL1LMNAF2ADORA1F12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114173772-A | Inhibitors of CD40-CD154 binding | 托尼克斯医药控股公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-1356977-A | Glucagon antagonists/inverse agonists | NOVO NORDISK AS (DK) | 2002-07-03 | — | — | CN | disclosed |
| EP-1183229-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000069810-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-11-23 | — | — | WO | disclosed |