Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 7/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 7/20 | 0.49 |
| ▸ | CDK2 | P24941 | 7/20 | 0.49 |
| ▸ | CDK9 | P50750 | 7/20 | 0.49 |
| ▸ | CDK1 | P06493 | 4/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.49 |
| ▸ | CDK7 | P50613 | 3/20 | 0.49 |
| ▸ | CCNH | P51946 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2655735 | 0.88 | MAPT (0.48) | NPC1PKMCCNT1CCNA2CDK2 | |
| SCHEMBL2655224 | 0.86 | CCNT1 (0.45) | CCNT1CCNA2CDK2CDK9CDK1 | |
| SCHEMBL2655693 | 0.86 | GAA (0.52) | NPC1PKMCCNT1CCNA2CDK2 | |
| SCHEMBL2656292 | 0.85 | LMNA (0.52) | CCNT1CCNA2CDK2CDK9CDK1 | |
| SCHEMBL13917349 | 0.84 | NPC1 (0.47) | NPC1PKMCCNT1CCNA2CDK2 | |
| SCHEMBL2656495 | 0.83 | ALDH1A1 (0.48) | NPC1PKMGFERCA12CA1 | |
| SCHEMBL4199937 | 0.82 | SCN9A (0.45) | CCNT1CCNA2CDK2CDK9CDK1 | |
| SCHEMBL4202254 | 0.82 | KDM4E (0.42) | CCNT1CCNA2CDK2CDK9CDK1 | |
| SCHEMBL2654719 | 0.82 | CCNT1 (0.42) | CCNT1CCNA2CDK2CDK9CDK1 | |
| SCHEMBL2654981 | 0.82 | SMN1; SMN2 (0.51) | CCNT1CCNA2CDK2CDK9CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090062304-A1 | Benzimidazole derivatives and their use for modulating the gaba-alpha receptor complex | NEUROSEARCH A/S (DK) | 2009-03-05 | — | — | US | disclosed |
| EP-1874735-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | NEUROSEARCH A/S (DK) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006111517-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | NEUROSEARCH A/S (DK) | 2006-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062304-A1 | Benzimidazole derivatives and their use for modulating the gaba-alpha receptor complex | GABRB1, GABRB2, GABRB3 | NPC1 1879/4885PKM 497/4885CCNT1 4531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.