SCHEMBL26536237

SCHEMBL26536237

CC(C)(C)c1ccccc1-n1c2ccc(-c3cc(-c4cc(C(F)(F)F)c(C(F)(F)F)c(C(F)(F)F)c4)cc(-c4cc(C(F)(F)F)c(C(F)(F)F)c(C(F)(F)F)c4)c3)cc2c2cc(-c3cc(-c4cc(C(F)(F)F)c(C(F)(F)F)c(C(F)(F)F)c4)cc(-c4cc(C(F)(F)F)c(C(F)(F)F)c(C(F)(F)F)c4)c3)ccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.34
ALDH1A1 P00352 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
HSD11B1 P28845 1/20 0.32
LDHA P00338 2/20 0.32
POLB P06746 1/20 0.31
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
ICMT O60725 1/20 0.30
TP53 P04637 1/20 0.30
AR P10275 1/20 0.30
RORC P51449 1/20 0.30
HCAR1 Q9BXC0 1/20 0.30
USP2 O75604 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26529200 0.91 ALDH1A1 (0.32) ALDH1A1L3MBTL1NR1H2NR1H3
SCHEMBL26536136 0.89 TRPA1 (0.43) TRPA1ALDH1A1HSD11B1TP53AR
SCHEMBL26529231 0.88 RBP4 (0.31)
SCHEMBL26536235 0.87 ICMT (0.41) TRPA1ALDH1A1L3MBTL1HSD11B1ICMT
SCHEMBL26536142 0.87 KIF11 (0.39) HSD11B1ICMT
SCHEMBL26529135 0.86 HSD11B1 (0.42) TRPA1ALDH1A1L3MBTL1MAPTKDM4E
SCHEMBL26529137 0.86 ALDH1A1 (0.37) TRPA1ALDH1A1L3MBTL1MAPTKDM4E
SCHEMBL26532282 0.86 ICMT (0.41) TRPA1ALDH1A1L3MBTL1HSD11B1ICMT
SCHEMBL26529253 0.85 GRM2 (0.35)
SCHEMBL26529188 0.85 GRM2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same P&h Tech Co., Ltd. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329101-A1 Organic Light Emitting Compound And Organic Light Emitting Device Including Same ORMDL3, OR10J3, ORC3 TRPA1 42/4885ALDH1A1 70/4885L3MBTL1 826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.