Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12793852 | 0.84 | ALDH1A1 (0.78) | ALDH1A1PRMT1GAALMNATSHR | |
| SCHEMBL29531346 | 0.84 | ALDH1A1 (0.78) | ALDH1A1PRMT1GAALMNATSHR | |
| SCHEMBL1169648 | 0.83 | ALDH1A1 (1.00) | ALDH1A1PRMT1GAALMNATSHR | |
| SCHEMBL1873887 | 0.81 | PRMT1 (0.77) | ALDH1A1PRMT1GAALMNATSHR | |
| SCHEMBL30833461 | 0.81 | MMP2 (0.50) | ALDH1A1PRMT1GAALMNATSHR | |
| SCHEMBL12059017 | 0.80 | ALDH1A1 (0.71) | ALDH1A1PRMT1GAALMNATSHR | |
| SCHEMBL18450372 | 0.79 | ALDH1A1 (0.68) | ALDH1A1LMNAPOLBSMN1; SMN2ATM | |
| SCHEMBL15822958 | 0.79 | PRMT1 (1.00) | ALDH1A1PRMT1GAALMNATSHR | |
| SCHEMBL9305676 | 0.79 | PRMT1 (0.74) | ALDH1A1PRMT1GAALMNATSHR | |
| SCHEMBL1169464 | 0.79 | PRMT1 (0.74) | ALDH1A1PRMT1GAALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322715-A1 | BROAD SPECTRUM ANTI-CANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322715-A1 | BROAD SPECTRUM ANTI-CANCER COMPOUNDS | YTHDF1, YTHDF3, YTHDF2 | ALDH1A1 4553/4885PRMT1 1115/4885GAA 1944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.