Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30855010 | 0.83 | ALDH1A1 (0.55) | MAPTALDH1A1KDM4EGAAPDE4A | |
| SCHEMBL26545931 | 0.81 | ALDH1A1 (0.48) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL26546033 | 0.81 | ALOX12 (0.67) | ALDH1A1GAAMEN1KMT2AALOX12 | |
| SCHEMBL16646057 | 0.79 | ALOX12 (0.69) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL26545834 | 0.77 | GAA (0.71) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL26545970 | 0.73 | ALOX12 (0.51) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL30854961 | 0.72 | HIF1A (0.59) | HIF1AMAPTALDH1A1KDM4EGAA | |
| SCHEMBL26545845 | 0.72 | MAPT (0.47) | HIF1AMAPTALDH1A1KDM4EGAA | |
| SCHEMBL26545899 | 0.72 | ILK (0.44) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL30854977 | 0.71 | ROCK2 (0.49) | ALDH1A1KDM4EGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3054936-B1 | 4-((2-HYDROXY-3-METHOXYBENZYL)AMINO) BENZENESULFONAMIDE DERIVATIVES AS 12-LIPOXYGENASE INHIBITORS | EASTERN VIRGINIA MEDICAL SCHOOL (US) | 2023-10-18 | — | — | EP | disclosed |