Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26552250 | 0.86 | GABRA1 (0.41) | TRPA1GABRA1GABRG2GABRB3LMNA | |
| SCHEMBL26552260 | 0.82 | GABRA1 (0.40) | TRPA1GABRA1GABRG2GABRB3LMNA | |
| SCHEMBL4656320 | 0.81 | ALDH1A1 (0.61) | TRPA1LMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL13710832 | 0.80 | ALDH1A1 (0.56) | GABRA1GABRG2GABRB3LMNAALDH1A1 | |
| SCHEMBL26552234 | 0.79 | ALDH1A1 (0.53) | TRPA1GABRA1GABRG2GABRB3LMNA | |
| SCHEMBL26552233 | 0.76 | MAPT (0.54) | LMNANFE2L2MAPTCYP1A2CYP3A4 | |
| SCHEMBL11761824 | 0.75 | GABRA1 (0.58) | TRPA1GABRA1GABRG2GABRB3LMNA | |
| SCHEMBL11761830 | 0.75 | GABRA1 (0.58) | TRPA1GABRA1GABRG2GABRB3LMNA | |
| SCHEMBL13969038 | 0.74 | ALDH1A1 (0.50) | GABRA1GABRG2GABRB3LMNAALDH1A1 | |
| SCHEMBL13710861 | 0.74 | ALDH1A1 (0.50) | GABRA1GABRG2GABRB3LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025895-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-01-25 | — | — | US | disclosed |
| US-11787804-B2 | Compositions and methods for modulating hair growth | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787804-B2 | Compositions and methods for modulating hair growth | PC, FH, SLC25A1 | TRPA1 2663/4885GABRA1 3526/4885GABRG2 2689/4885 |
| US-20240025895-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | PC, FH, SLC25A1 | TRPA1 2663/4885GABRA1 3526/4885GABRG2 2689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.