Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14166842 | 0.80 | NOS1 (0.41) | FFAR2 | |
| SCHEMBL7554129 | 0.75 | CA2 (0.35) | — | |
| SCHEMBL1007892 | 0.67 | ALDH1A1 (0.42) | FFAR2 | |
| SCHEMBL29457012 | 0.64 | APLNR (0.54) | FFAR2EPHX1APP | |
| SCHEMBL29457029 | 0.64 | APP (0.37) | EPHX1APP | |
| Acetic Acid SCHEMBL15573203 | 0.64 | NQO2 (0.37) | FFAR2 | |
| SCHEMBL29376655 | 0.63 | APP (0.36) | EPHX1APP | |
| SCHEMBL279947 | 0.63 | FFAR2 (0.42) | FFAR2 | |
| SCHEMBL30598651 | 0.63 | LMNA (0.36) | FFAR2EPHX1 | |
| SCHEMBL19734432 | 0.62 | APP (0.38) | EPHX1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001875-A2 | GLUCOKINASE ACTIVATORS | Takeda San Diego, Inc. (US) | 2008-12-17 | — | — | EP | claimed |
| WO-2007104034-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-09-13 | — | — | WO | claimed |
| EP-2001875-A2 | GLUCOKINASE ACTIVATORS | Takeda San Diego, Inc. (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007104034-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-09-13 | — | — | WO | disclosed |