Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 1/20 | 0.32 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2660519 | 0.92 | HDAC3 (0.35) | LGALS8LGALS3KDM4EMAPT | |
| SCHEMBL2661758 | 0.90 | LGALS8 (0.32) | LGALS8LGALS3KDM4ENPC1RAB9A | |
| SCHEMBL2659767 | 0.88 | PYGL (0.32) | LGALS8LGALS3MEN1KMT2APYGL | |
| SCHEMBL2661327 | 0.88 | PLA2G7 (0.31) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2660397 | 0.86 | MCL1 (0.31) | LGALS8LGALS3PYGL | |
| SCHEMBL2659747 | 0.86 | MCL1 (0.31) | LGALS8LGALS3PYGL | |
| SCHEMBL2660563 | 0.81 | HDAC3 (0.36) | MAPT | |
| SCHEMBL2659947 | 0.80 | ALDH1A1 (0.40) | NPC1 | |
| SCHEMBL2659987 | 0.79 | LGALS8 (0.33) | LGALS8LGALS3KDM4EKMT2A | |
| SCHEMBL2660055 | 0.79 | MAPT (0.39) | KDM4EMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074119-A1 | INDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |