Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.32 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.30 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2661098 | 0.78 | NR1H2 (0.30) | — | |
| SCHEMBL13221832 | 0.76 | — | — | |
| SCHEMBL2659966 | 0.75 | XDH (0.35) | — | |
| SCHEMBL2966007 | 0.74 | GLO1 (0.41) | — | |
| SCHEMBL2659602 | 0.73 | — | — | |
| SCHEMBL2660728 | 0.72 | TUBB4A (0.37) | CXCR2CXCR4 | |
| SCHEMBL2660615 | 0.68 | SLC40A1 (0.47) | CXCR2CXCR4 | |
| SCHEMBL2660310 | 0.66 | OXTR (0.33) | — | |
| SCHEMBL2660421 | 0.66 | LMNA (0.45) | CXCR2 | |
| SCHEMBL2969566 | 0.65 | GLO1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074119-A1 | INDOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008050821-A1 | INDOLE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-02 | — | — | WO | disclosed |