Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29825595 | 1.00 | TDP1 (0.34) | TDP1GPBAR1TAAR1ALDH1A1LMNA | |
| SCHEMBL25184024 | 0.81 | TDP1 (0.38) | TDP1GPBAR1TAAR1ALDH1A1LMNA | |
| SCHEMBL19737924 | 0.79 | RECQL (0.39) | TDP1GPBAR1TAAR1ALDH1A1LMNA | |
| SCHEMBL18519051 | 0.79 | NOS3 (0.38) | TDP1GPBAR1TAAR1ALDH1A1LMNA | |
| SCHEMBL844244 | 0.78 | MPO (0.36) | TAAR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL23847865 | 0.77 | PRKCI (0.31) | ALDH1A1LMNASMN1; SMN2 | |
| Bromide SCHEMBL959014 | 0.77 | MPO (0.35) | TAAR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL30949974 | 0.76 | TDP1 (0.35) | TDP1TAAR1 | |
| SCHEMBL31280885 | 0.75 | ALDH1A1 (0.30) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL31667708 | 0.75 | NOS2 (0.42) | TAAR1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250296939-A1 | BENZOTHIOPHENE COMPOUND | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2025-09-25 | — | — | US | disclosed |
| EP-4516792-A1 | BENZOTHIOPHENE COMPOUND | Kyoto Pharmaceutical Industries, Ltd. (JP) | 2025-03-05 | — | — | EP | disclosed |
| WO-2023210740-A1 | BENZOTHIOPHENE COMPOUND | 第一三共株式会社 | 2023-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250296939-A1 | BENZOTHIOPHENE COMPOUND | NFE2L2, KEAP1, BPTF | TDP1 3406/4885GPBAR1 930/4885TAAR1 3615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.