Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 4/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | USP1 | O94782 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | YAP1 | P46937 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30643684 | 0.88 | OPRD1 (0.42) | PRMT5CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL26641508 | 0.86 | OPRD1 (0.41) | PRMT5CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL30830739 | 0.85 | PARP1 (0.42) | PRMT5CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL25940751 | 0.83 | PARP1 (0.43) | PRMT5CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL30136015 | 0.83 | PARP1 (0.43) | PRMT5CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL26642195 | 0.83 | TLR9 (0.46) | PRMT5CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL26641553 | 0.82 | OPRD1 (0.42) | PRMT5CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL29197031 | 0.81 | PRMT5 (0.48) | PRMT5CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL26641237 | 0.81 | PRMT5 (0.39) | PRMT5CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL25035220 | 0.81 | CYP11B2 (0.42) | PRMT5CCNT1CCNA2CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120092003-A | CDK protein degrading agents, pharmaceutical compositions and therapeutic uses | 拜欧斯瑞克斯公司 | 2025-06-03 | — | — | CN | disclosed |
| WO-2023220640-A1 | CDK PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-11-16 | — | — | WO | disclosed |