Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | YAP1 | P46937 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26641237 | 0.93 | PRMT5 (0.39) | OPRD1OPRK1PRMT5CCNT1CCNA2 | |
| SCHEMBL26641508 | 0.90 | OPRD1 (0.41) | OPRD1OPRK1PRMT5TACR1CCNT1 | |
| SCHEMBL26641523 | 0.89 | GRM5 (0.37) | — | |
| SCHEMBL26641379 | 0.88 | PRMT5 (0.40) | OPRD1OPRK1PRMT5TACR1CCNT1 | |
| SCHEMBL26641553 | 0.87 | OPRD1 (0.42) | OPRD1OPRK1PRMT5TACR1CCNT1 | |
| SCHEMBL26641448 | 0.86 | CYP46A1 (0.43) | OPRD1OPRK1PRMT5GPR119ACHE | |
| SCHEMBL27039398 | 0.85 | OPRD1 (0.45) | OPRD1OPRK1PRMT5TACR1CCNT1 | |
| SCHEMBL26641295 | 0.84 | YAP1 (0.38) | OPRD1OPRK1PRMT5CCNT1CCNA2 | |
| SCHEMBL30643651 | 0.84 | YAP1 (0.38) | OPRD1OPRK1PRMT5CCNT1CCNA2 | |
| SCHEMBL30830495 | 0.83 | GPR119 (0.47) | OPRD1OPRK1PRMT5GPR119ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120092003-A | CDK protein degrading agents, pharmaceutical compositions and therapeutic uses | 拜欧斯瑞克斯公司 | 2025-06-03 | — | — | CN | disclosed |
| WO-2023220640-A1 | CDK PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-11-16 | — | — | WO | disclosed |