Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 11/20 | 0.59 |
| ▸ | FNTB | P49356 | 11/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26665757 | 0.90 | FNTA (0.58) | FNTAFNTBCA12CA1CA2 | |
| SCHEMBL26665760 | 0.90 | FNTA (0.64) | FNTAFNTBCA12CA1CA2 | |
| SCHEMBL26665770 | 0.89 | FNTA (0.51) | FNTAFNTBCA12CA1CA2 | |
| SCHEMBL26665763 | 0.89 | FNTA (0.59) | FNTAFNTBCA12CA1CA2 | |
| SCHEMBL26829996 | 0.87 | ALDH1A1 (0.52) | FNTAFNTBNPC1RAB9ANPSR1 | |
| SCHEMBL26665754 | 0.86 | FNTA (0.48) | FNTAFNTBCA12CA1CA2 | |
| SCHEMBL26665759 | 0.82 | FNTA (0.46) | FNTAFNTBCA12CA1CA2 | |
| SCHEMBL26830001 | 0.78 | ALDH1A1 (0.54) | FNTAFNTBCA12CA1CA2 | |
| SCHEMBL26829993 | 0.78 | ALDH1A1 (0.57) | FNTAFNTBNPC1RAB9ANPSR1 | |
| SCHEMBL26829999 | 0.77 | ALDH1A1 (0.52) | FNTAFNTBNPSR1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11981673-B1 | 7-isopropyl 1,2-dimethyl 3-(substituted benzoyl)indolizine-1,2,7 tricarboxylates as adenosine receptor active compounds | King Faisal University (SA) | 2024-05-14 | — | — | US | claimed |
| US-11807640-B1 | 7-isopropyl 1-ethyl/methyl 3-(substituted benzoyl)-2-substituted indolizine-1,7-dicarboxylates as anti-tubercular agents | King Faisal University (SA) | 2023-11-07 | — | — | US | claimed |
| US-11981674-B1 | 7-isopropyl 1-ethyl/methyl 3-(substituted benzoyl)-2-substituted indolizine-1,7-dicarboxylates as larvicidal agents | King Faisal University (SA) | 2024-05-14 | — | — | US | disclosed |
| US-11981673-B1 | 7-isopropyl 1,2-dimethyl 3-(substituted benzoyl)indolizine-1,2,7 tricarboxylates as adenosine receptor active compounds | King Faisal University (SA) | 2024-05-14 | — | — | US | disclosed |
| US-11807640-B1 | 7-isopropyl 1-ethyl/methyl 3-(substituted benzoyl)-2-substituted indolizine-1,7-dicarboxylates as anti-tubercular agents | King Faisal University (SA) | 2023-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11981674-B1 | 7-isopropyl 1-ethyl/methyl 3-(substituted benzoyl)-2-substituted indolizine-1,7-dicarboxylates as larvicidal agents | CASP7, CASP3, CASP2 | FNTA 2187/4885FNTB 2405/4885CA12 4810/4885 |
| US-11981673-B1 | 7-isopropyl 1,2-dimethyl 3-(substituted benzoyl)indolizine-1,2,7 tricarboxylates as adenosine receptor active compounds | ADORA3, ADORA2A, ADORA1 | FNTA 3213/4885FNTB 2090/4885CA12 4773/4885 |
| US-11807640-B1 | 7-isopropyl 1-ethyl/methyl 3-(substituted benzoyl)-2-substituted indolizine-1,7-dicarboxylates as anti-tubercular agents | IRF3, TBK1, TBKBP1 | FNTA 1843/4885FNTB 508/4885CA12 4768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.