Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 18/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodophenpropit SCHEMBL114508 | 0.81 | HRH4 (1.00) | HRH4TP53CYP1A2CYP3A4MEN1 | |
| Iodophenpropit SCHEMBL22651297 | 0.81 | HRH4 (1.00) | HRH4TP53CYP1A2CYP3A4MEN1 | |
| SCHEMBL8805366 | 0.79 | HRH4 (0.63) | HRH4TP53CYP1A2CYP3A4MEN1 | |
| SCHEMBL8621926 | 0.69 | HRH3 (0.60) | HRH4TP53CYP1A2CYP3A4MEN1 | |
| SCHEMBL8620794 | 0.66 | HRH3 (0.56) | HRH4TP53CYP1A2CYP3A4MEN1 | |
| SCHEMBL8619886 | 0.64 | HRH4 (0.61) | HRH4TP53CYP1A2CYP3A4MEN1 | |
| SCHEMBL8805742 | 0.63 | HRH4 (0.54) | HRH4TP53CYP1A2CYP3A4MEN1 | |
| SCHEMBL8625836 | 0.63 | HRH3 (0.63) | HRH4TP53CYP1A2CYP3A4MEN1 | |
| SCHEMBL7003873 | 0.62 | GPR84 (0.41) | HRH3 | |
| SCHEMBL11826939 | 0.62 | MAOA (0.36) | HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230346879-A1 | COMPOSITIONS AND METHODS FOR COMBINATORIAL DRUG DISCOVERY IN NANOLITER DROPLETS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230346879-A1 | COMPOSITIONS AND METHODS FOR COMBINATORIAL DRUG DISCOVERY IN NANOLITER DROPLETS | RAB5IF, CLTB, TBK1 | HRH4 4196/4885TP53 2153/4885CYP1A2 4441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.