Iodophenpropit

Iodophenpropit

SCHEMBL114508

NC(=NCCc1ccc(I)cc1)SCCCc1cnc[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 20/20 1.00
TP53 P04637 2/20 1.00
CYP1A2 P05177 2/20 1.00
CYP3A4 P08684 2/20 1.00
MEN1 O00255 1/20 1.00
TSHR P16473 1/20 1.00
KMT2A Q03164 1/20 1.00
HRH3 Q9Y5N1 19/20 0.98
CYP2D6 P10635 1/20 0.64
CYP2C9 P11712 1/20 0.64
CYP2C19 P33261 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodophenpropit SCHEMBL22651297 1.00 HRH4 (1.00) HRH4TP53CYP1A2CYP3A4MEN1
Iodophenpropit SCHEMBL30632137 0.99 HRH4 (1.00) HRH4TP53CYP1A2CYP3A4MEN1
SCHEMBL26687384 0.81 HRH4 (0.69) HRH4TP53CYP1A2CYP3A4MEN1
Clobenpropit SCHEMBL49050 0.78 HRH4 (1.00) HRH4TP53CYP1A2CYP3A4MEN1
SCHEMBL9534159 0.78 HRH4 (1.00) HRH4TP53CYP1A2CYP3A4HRH3
SCHEMBL8805366 0.77 HRH4 (0.63) HRH4TP53CYP1A2CYP3A4MEN1
SCHEMBL9533886 0.71 HRH4 (0.58) HRH4TP53CYP1A2CYP3A4MEN1
SCHEMBL7859117 0.67 HRH4 (1.00) HRH4HRH3
SCHEMBL8621926 0.65 HRH3 (0.60) HRH4TP53CYP1A2CYP3A4MEN1
Clobenpropit SCHEMBL19733457 0.63 HRH4 (0.65) HRH4TP53CYP1A2CYP3A4HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1687 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250085273-A1 NOVEL RAPID DRUG DISCOVERY FOR SEPSIS AND AGENTS FOR USE AS SEPSIS THERAPY THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY 2025-03-13 US claimed
CN-101662966-A packages for ophthalmic lenses containing pharmaceutical agents JOHNSON & JOHNSON VISION CARE 2010-03-03 CN claimed
EP-2046872-A2 PACKAGES FOR OPHTHALMIC LENSES CONTAINING PHARMACEUTICAL AGENTS Johson & Johnson Vision Care Inc. (US) 2009-04-15 EP claimed
US-20080023345-A1 PACKAGES FOR OPHTHALMIC LENSES CONTAINING PHARMACEUTICAL AGENTS JOHNSON & JOHNSON VISION CARE, INC. 2008-01-31 US claimed
WO-2008008636-A2 PACKAGES FOR OPHTHALMIC LENSES CONTAINING PHARMACEUTICAL AGENTS JOHNSON & JOHNSON VISION CARE, INC. (US) 2008-01-17 WO claimed
WO-2002036114-A1 COMPOSITION COMPRISING SEROTONIN RECEPTOR ANTAGONISTS, 5 HT-2 AND 5 HT-3 RESPIRATORIUS AB (SE) 2002-05-10 WO claimed
WO-2001095902-A9 A COMPOSITION COMPRISING A COMBINATION OF RECEPTOR AGONISTS AND ANTAGONISTS 2002-04-25 WO claimed
WO-2001095902-A1 A COMPOSITION COMPRISING A COMBINATION OF RECEPTOR AGONISTS AND ANTAGONISTS RESPIRATORIUS AB (SE) 2001-12-20 WO claimed
WO-2001095903-A1 5-HT3 RECEPTOR ANTAGONISTS FOR TREATMENT OF DISORDERS INVOLVING AIRWAY CONSTRICTION RESPIRATORIUS AB (SE) 2001-12-20 WO claimed
EP-4199925-B1 CYCLOPENTAPYRROLE OREXIN RECEPTOR AGONISTS MERCK SHARP & DOHME LLC (US) 2026-05-20 EP disclosed
US-20260124192-A1 COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING RNA VIRAL INFECTIONS MODEL MEDICINES INC (US) 2026-05-07 US disclosed
US-20260102384-A1 USE OF PIPENDOXIFENE FOR TREATING INFECTIONS OF DNA VIRUSES MODEL MEDICINES INC (US) 2026-04-16 US disclosed
EP-3558298-B1 ANTIDIABETIC SPIROCHROMAN COMPOUNDS MERCK SHARP & DOHME LLC (US) 2026-03-11 EP disclosed
US-20260053829-A1 COMPOSITIONS AND METHODS FOR IMPROVING COGNITIVE FUNCTION DIAMOND THERAPEUTICS INC (CA) 2026-02-26 US disclosed
WO-2002036113-A1 COMPOSITION COMPRISING: SEROTONIN RECEPTOR ANTAGONISTS (5HT-2, 5HT-3) AND AGONIST (5HT-4) RESPIRATORIUS AB (SE) 2002-05-10 WO disclosed
WO-2001095902-A9 A COMPOSITION COMPRISING A COMBINATION OF RECEPTOR AGONISTS AND ANTAGONISTS 2002-04-25 WO disclosed
CN-1343924-A Chinese-character 'first pyhonetic letter table-shape code' encode method and its keyboard QIN RONGFU (CN) 2002-04-10 CN disclosed
WO-2001095902-A1 A COMPOSITION COMPRISING A COMBINATION OF RECEPTOR AGONISTS AND ANTAGONISTS RESPIRATORIUS AB (SE) 2001-12-20 WO disclosed
WO-2001085786-A2 HUMAN HISTAMINE H4 RECEPTOR WYETH (US) 2001-11-15 WO disclosed
CN-1283108-A Chlamydia protein, gene sequence and use thereof ANTEX BIOLOFICS INC (US) 2001-02-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260053829-A1 COMPOSITIONS AND METHODS FOR IMPROVING COGNITIVE FUNCTION HTR1A, HTR5A, HTR3B HRH4 445/4885TP53 3804/4885CYP1A2 1238/4885
US-20260102384-A1 USE OF PIPENDOXIFENE FOR TREATING INFECTIONS OF DNA VIRUSES ESR1, VDR, POLL HRH4 4405/4885TP53 884/4885CYP1A2 733/4885
US-20260124192-A1 COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING RNA VIRAL INFECTIONS SARS1, NSUN2, NSUN3 HRH4 4319/4885TP53 2128/4885CYP1A2 745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.