SCHEMBL26696502

SCHEMBL26696502

CN(CCN(C)C(=O)OC(C)(C)C)C(=O)Oc1ccc(OCc2ccccc2)c(OCc2ccccc2)c1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.42
LTB4R Q15722 2/20 0.41
LTB4R2 Q9NPC1 2/20 0.41
HIF1A Q16665 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
EGFR P00533 2/20 0.41
HTR2C P28335 2/20 0.41
SLC6A4 P31645 2/20 0.41
ACHE P22303 1/20 0.41
APP P05067 2/20 0.40
ALOX5 P09917 1/20 0.40
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25725323 0.91 PDK2 (0.41) PDK2LTB4RLTB4R2L3MBTL1EGFR
SCHEMBL24344772 0.89 FFAR4 (0.42) PDK2LTB4RLTB4R2L3MBTL1EGFR
SCHEMBL26691734 0.85 L3MBTL1 (0.42) PDK2HIF1AMEN1KMT2AL3MBTL1
Bromide SCHEMBL30195582 0.83 L3MBTL1 (0.39) PDK2HIF1AL3MBTL1HTR2CSLC6A4
SCHEMBL25725295 0.79 GBA1 (0.46) PDK2MEN1KMT2AL3MBTL1HTR2C
SCHEMBL26691721 0.79 KDM4E (0.40) PDK2KMT2AACHEKDM4ELMNA
SCHEMBL7646792 0.78 HTR1A (0.51) LTB4RLTB4R2L3MBTL1
SCHEMBL3014165 0.78 LTB4R (0.67) LTB4RLTB4R2EGFRALOX5
SCHEMBL26691712 0.77 PDK2 (0.42) PDK2EGFRACHE
SCHEMBL4454375 0.77 FFAR1 (0.59) LTB4RLTB4R2MEN1KMT2AAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4373813-A1 COMPOUNDS AND METHODS FOR DETECTION OF SUPEROXIDE PROMEGA CORPORATION (US) 2024-05-29 EP disclosed
US-11802114-B2 Compounds and methods for detection of superoxide PROMEGA CORPORATION (US) 2023-10-31 US disclosed
WO-2023004046-A1 COMPOUNDS AND METHODS FOR DETECTION OF SUPEROXIDE PROMEGA CORPORATION (US) 2023-01-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11802114-B2 Compounds and methods for detection of superoxide SOD1, GPX4, SOD3 PDK2 487/4885LTB4R 1459/4885LTB4R2 1493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.