SCHEMBL26698336

SCHEMBL26698336

CCO[Si](CCCNC(=O)NCCCN1CCN(C)CC1)(OCC)OCC

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.44
HSD17B10 Q99714 1/20 0.44
USP2 O75604 1/20 0.44
MAPT P10636 4/20 0.43
TP53 P04637 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
PAOX Q6QHF9 1/20 0.39
CNR1 P21554 1/20 0.39
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26601910 0.86 ALDH1A1 (0.54) KDM4EMAPTSMN1; SMN2ALDH1A1
SCHEMBL329695 0.82 PAOX (0.38) USP2PAOXALDH1A1
SCHEMBL2561394 0.82 EPHX1 (0.48) KMT2A
SCHEMBL2616667 0.81 TDP1 (0.49) KDM4ESMN1; SMN2CNR1ALDH1A1
SCHEMBL33525089 0.80 CNR1 (0.46) KMT2AKDM4EHSD17B10MAPTSMN1; SMN2
SCHEMBL4419366 0.80 EPHX1 (0.47) KMT2A
SCHEMBL13529065 0.79 ACHE (0.46) USP2TP53SMN1; SMN2
SCHEMBL4362272 0.78 EPHX1 (0.55) KDM4E
SCHEMBL17133248 0.77 EPHX1 (0.41) KMT2A
SCHEMBL4355762 0.77 EPHX1 (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4511484-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR ISOLATION OF NUCLEIC ACIDS Promega Corporation (US) 2025-02-26 EP disclosed
CN-119095959-A Compounds, compositions and methods for isolating nucleic acids 普罗美加公司 2024-12-06 CN disclosed
US-20230382875-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR ISOLATION OF NUCLEIC ACIDS PROMEGA CORPORATION 2023-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230382875-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR ISOLATION OF NUCLEIC ACIDS POLRMT, POLN, NOP2 KMT2A 2369/4885KDM4E 4054/4885HSD17B10 2186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.