Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8018941 | 0.88 | CYP2D6 (0.70) | CYP2D6CYP3A4CXCR4ALDH1A1ALOX15 | |
| SCHEMBL26708819 | 0.83 | CYP3A4 (0.67) | CYP2D6CYP3A4CXCR4ALDH1A1ALOX15 | |
| SCHEMBL26708921 | 0.81 | L3MBTL1 (0.59) | CYP2D6CYP3A4CXCR4ALDH1A1ALOX15 | |
| SCHEMBL5595366 | 0.81 | CYP2D6 (0.59) | CYP2D6CYP3A4ALDH1A1ALOX15TSHR | |
| SCHEMBL26708784 | 0.78 | L3MBTL1 (0.77) | CYP2D6CYP3A4CXCR4ALDH1A1ALOX15 | |
| SCHEMBL6538443 | 0.78 | DPP7 (0.65) | CYP2D6CYP3A4ALDH1A1CHRM2CYP1A2 | |
| SCHEMBL26708829 | 0.77 | L3MBTL1 (0.51) | CYP2D6CYP3A4CXCR4ALDH1A1ALOX15 | |
| SCHEMBL26143789 | 0.76 | L3MBTL1 (0.61) | CYP2D6CYP3A4CXCR4ALDH1A1ALOX15 | |
| SCHEMBL4048999 | 0.75 | CYP2D6 (0.59) | CYP2D6CYP3A4ALDH1A1L3MBTL1CHRM2 | |
| SCHEMBL26708798 | 0.75 | CXCR4 (0.48) | CYP2D6CYP3A4CXCR4ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230346769-A1 | USE OF SIMPLE ACYCLIC POLYAMINES FOR THE TREATMENT OF DISEASES CAUSED BY PARASITES OF THE GENUS LEISHMANIA | UNIVERSIDAD DE GRANADA (ES) | 2023-11-02 | — | — | US | disclosed |
| US-20230346769-A1 | USE OF SIMPLE ACYCLIC POLYAMINES FOR THE TREATMENT OF DISEASES CAUSED BY PARASITES OF THE GENUS LEISHMANIA | UNIVERSIDAD DE GRANADA (ES) | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230346769-A1 | USE OF SIMPLE ACYCLIC POLYAMINES FOR THE TREATMENT OF DISEASES CAUSED BY PARASITES OF THE GENUS LEISHMANIA | SRM, SMS, ARG2 | CYP2D6 2218/4885CYP3A4 3155/4885CXCR4 2868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.