Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 3/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 4/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16805207 | 0.95 | GPR84 (0.36) | ENPP1THRATHRBGPR84ESR1 | |
| SCHEMBL16352625 | 0.91 | ALDH1A1 (0.42) | ENPP1GPR84ESR1ESR2TNF | |
| SCHEMBL12023379 | 0.91 | ALDH1A1 (0.42) | ENPP1GPR84ESR1ESR2TNF | |
| SCHEMBL16352619 | 0.91 | ALDH1A1 (0.42) | ENPP1GPR84ESR1ESR2TNF | |
| SCHEMBL26761119 | 0.91 | ENPP1 (0.43) | ENPP1TNFENPP3KDM4EALDH1A1 | |
| SCHEMBL17935584 | 0.90 | ENPP1 (0.45) | ENPP1TNFENPP3KDM4EALDH1A1 | |
| SCHEMBL17934708 | 0.90 | ENPP1 (0.45) | ENPP1ESR1ESR2TNFENPP3 | |
| SCHEMBL126261 | 0.89 | ALDH1A1 (0.40) | ENPP1GPR84ESR1ESR2ENPP3 | |
| SCHEMBL17935585 | 0.89 | ALDH1A1 (0.40) | ENPP1GPR84ESR1ESR2ENPP3 | |
| SCHEMBL126429 | 0.89 | ALDH1A1 (0.40) | ENPP1GPR84ESR1ESR2ENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230371376-A1 | POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME | SFC CO., LTD. (KR) | 2023-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230371376-A1 | POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME | PPOX, MAP1LC3A, VDAC2 | ENPP1 2699/4885THRA 3696/4885THRB 4415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.