SCHEMBL16805207

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26761796	0.95	ENPP1 (0.38)	GPR84ACHEESR1ESR2ENPP1
	SCHEMBL16263483	0.89	ACHE (0.38)	GPR84ACHEESR1ESR2ENPP1
	SCHEMBL19654605	0.88	GPR84 (0.37)	GPR84ESR1ESR2KDM4EMEN1
	SCHEMBL17934707	0.87	ACHE (0.39)	GPR84ACHEESR1ESR2KDM4E
	SCHEMBL16352625	0.87	ALDH1A1 (0.42)	GPR84ESR1ESR2ENPP1KDM4E
	SCHEMBL26761119	0.87	ENPP1 (0.43)	ENPP1KDM4EMAPTMAPK1TDP1
	SCHEMBL16352619	0.87	ALDH1A1 (0.42)	GPR84ESR1ESR2ENPP1KDM4E
	SCHEMBL12023379	0.87	ALDH1A1 (0.42)	GPR84ESR1ESR2ENPP1KDM4E
	SCHEMBL24840894	0.87	GPR84 (0.36)	GPR84ESR1ESR2KDM4EMEN1
	SCHEMBL13995133	0.86	COMT (0.39)	GPR84ENPP1KDM4EMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.