Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 6/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 2/20 | 0.42 |
| ▸ | CASP6 | P55212 | 2/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.41 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.41 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.41 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11347286 | 0.86 | TIMP3 (0.49) | MPLPRMT1CA1CA2CASP6 | |
| SCHEMBL11339069 | 0.83 | KMT2A (0.53) | PRMT1CA1CA2NSD2 | |
| SCHEMBL10396176 | 0.82 | MPL (0.53) | MPLLDHANSD2CASP6MMP14 | |
| SCHEMBL11339023 | 0.81 | CA12 (0.47) | PRMT1CA1CA2 | |
| SCHEMBL10907712 | 0.81 | MPL (0.46) | MPLPRMT1CA1CA2CASP6 | |
| SCHEMBL11435352 | 0.81 | CASP6 (0.55) | MPLPRMT1CA1CA2CASP6 | |
| SCHEMBL11348931 | 0.80 | HPSE (0.45) | MPLPRMT1CA1CA2NSD2 | |
| SCHEMBL10823467 | 0.79 | IDH1 (0.58) | CA1CA2 | |
| SCHEMBL10823484 | 0.79 | IDH1 (0.52) | PRMT1CA1CA2 | |
| SCHEMBL11207461 | 0.79 | KDM4E (0.49) | MPLPRMT1CA1CA2CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8175860-B2 | Method of inhibiting the growth of Helicobacter pylori | NATIONAL TSING HUA UNIVERSITY (TW) | 2012-05-08 | — | — | US | disclosed |
| US-20100305152-A1 | METHOD OF INHIBITING THE GROWTH OF HELICOBACTER PYLORI | NATIONAL TSING HUA UNIVERSITY (TW) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305152-A1 | METHOD OF INHIBITING THE GROWTH OF HELICOBACTER PYLORI | HPD, HAAO, HK1 | MPL 4334/4885PRMT1 3728/4885CA1 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.