SCHEMBL268064

SCHEMBL268064

Oc1nc(O)nc(Oc2ccccc2Br)n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.44
POLB P06746 2/20 0.44
GAA P10253 1/20 0.44
LMNA P02545 5/20 0.42
LCK P06239 1/20 0.38
MAPT P10636 5/20 0.37
MEN1 O00255 4/20 0.37
KDM4E B2RXH2 3/20 0.37
NPSR1 Q6W5P4 2/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
TTR P02766 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
ALDH1A1 P00352 2/20 0.36
USP2 O75604 1/20 0.36
TSHR P16473 1/20 0.36
GRM4 Q14833 2/20 0.36
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5968103 0.86 LMNA (0.44) KMT2APOLBGAALMNALCK
SCHEMBL28444543 0.77 KMT2A (0.44) KMT2APOLBGAALMNALCK
SCHEMBL3017058 0.76 ALOX15 (0.35) KMT2APOLBGAALMNAMAPT
SCHEMBL15916488 0.76 LMNA (0.55) KMT2APOLBGAALMNALCK
SCHEMBL6264432 0.74 KMT2A (0.45) KMT2APOLBGAALMNALCK
SCHEMBL15916364 0.74 LMNA (0.46) KMT2APOLBGAALMNALCK
SCHEMBL727333 0.73 ALDH1A1 (0.48) LMNALCKTTRSMN1; SMN2ALDH1A1
SCHEMBL8345483 0.72 ALOX15 (0.35) KMT2APOLBGAALMNAMAPT
SCHEMBL3842507 0.71 MAPK1 (0.46) LMNALCKTTRSMN1; SMN2ALDH1A1
SCHEMBL3737402 0.71 PAX8 (0.53) KMT2APOLBGAALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104710698-A THERMOPLASTIC RESIN COMPOSITION HAVING SUPERIOR FLAME RETARDANCY, COLORING PROPERTY AND SCRATCH-RESISTANCE LG CHEMICAL LTD 2015-06-17 CN claimed
US-8133942-B2 Thermoplastic resin composition having superior flame retardancy, coloring property and scratch-resistance LG CHEM, LTD. (KR) 2012-03-13 US claimed
US-20100069540-A1 THERMOPLASTIC RESIN COMPOSITION HAVING SUPERIOR FLAME RETARDANCY, COLORING PROPERTY AND SCRATCH-RESISTANCE LG CHEM, LTD. (KR) 2010-03-18 US claimed
CN-104710698-A THERMOPLASTIC RESIN COMPOSITION HAVING SUPERIOR FLAME RETARDANCY, COLORING PROPERTY AND SCRATCH-RESISTANCE LG CHEMICAL LTD 2015-06-17 CN disclosed
CN-104710698-A THERMOPLASTIC RESIN COMPOSITION HAVING SUPERIOR FLAME RETARDANCY, COLORING PROPERTY AND SCRATCH-RESISTANCE LG CHEMICAL LTD 2015-06-17 CN disclosed
US-8133942-B2 Thermoplastic resin composition having superior flame retardancy, coloring property and scratch-resistance LG CHEM, LTD. (KR) 2012-03-13 US disclosed
US-8133942-B2 Thermoplastic resin composition having superior flame retardancy, coloring property and scratch-resistance LG CHEM, LTD. (KR) 2012-03-13 US disclosed
JP-2010070760-A THERMOPLASTIC RESIN COMPOSITION EXCELLENT IN FLAME RETARDANCY, COLORABILITY AND SCRATCH RESISTANCE LG CHEM LTD 2010-04-02 JP disclosed
CN-101676328-A Thermoplastic resin composition having excellent flame retardancy, colorability and scratch resistance LG CHEMICAL LTD 2010-03-24 CN disclosed
US-20100069540-A1 THERMOPLASTIC RESIN COMPOSITION HAVING SUPERIOR FLAME RETARDANCY, COLORING PROPERTY AND SCRATCH-RESISTANCE LG CHEM, LTD. (KR) 2010-03-18 US disclosed
US-20100069540-A1 THERMOPLASTIC RESIN COMPOSITION HAVING SUPERIOR FLAME RETARDANCY, COLORING PROPERTY AND SCRATCH-RESISTANCE LG CHEM, LTD. (KR) 2010-03-18 US disclosed