SCHEMBL2681707

SCHEMBL2681707

CN(C)c1ccc(N=Nc2cccc([N+](=O)[O-])c2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 9/20 0.63
▸ ALDH1A1 P00352 8/20 0.63
▸ MEN1 O00255 8/20 0.63
▸ MAPT P10636 6/20 0.63
▸ MAPK1 P28482 3/20 0.63
▸ NPC1 O15118 7/20 0.62
▸ RAB9A P51151 7/20 0.62
▸ CASP3 P42574 2/20 0.62
▸ SENP8 Q96LD8 2/20 0.62
▸ SENP7 Q9BQF6 2/20 0.62
▸ SENP6 Q9GZR1 2/20 0.62
▸ TDP1 Q9NUW8 4/20 0.58
▸ NSD2 O96028 1/20 0.58
▸ NPSR1 Q6W5P4 1/20 0.56
▸ TSHR P16473 2/20 0.54
▸ HSD17B10 Q99714 1/20 0.54
▸ CA12 O43570 2/20 0.54
▸ CA2 P00918 2/20 0.54
▸ CA9 Q16790 2/20 0.54
▸ BAZ1A Q9NRL2 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4955530 1.00 KMT2A (0.63) KMT2AALDH1A1MEN1MAPTMAPK1
SCHEMBL2384564 0.84 MAPT (0.64) KMT2AALDH1A1MEN1MAPTMAPK1
SCHEMBL7987027 0.84 MAPT (0.64) KMT2AALDH1A1MEN1MAPTMAPK1
SCHEMBL2384567 0.84 MAPT (0.64) KMT2AALDH1A1MEN1MAPTMAPK1
SCHEMBL7987030 0.84 MAPT (0.64) KMT2AALDH1A1MEN1MAPTMAPK1
SCHEMBL1405486 0.83 TSHR (0.67) KMT2AALDH1A1MEN1MAPTMAPK1
SCHEMBL1405487 0.83 TSHR (0.67) KMT2AALDH1A1MEN1MAPTMAPK1
SCHEMBL1405402 0.82 NPC1 (0.65) KMT2AALDH1A1MEN1MAPTMAPK1
SCHEMBL1405403 0.82 NPC1 (0.65) KMT2AALDH1A1MEN1MAPTMAPK1
SCHEMBL4959902 0.81 ALDH1A1 (0.56) KMT2AALDH1A1MEN1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240268136-A1 QUANTUM DOT LIGHT-EMITTING DEVICE AND METHOD FOR PATTERNING QUANTUM DOT LAYER Beijing Boe Technology Development Co., Ltd. (CN) 2024-08-08 — — US disclosed
CN-117136639-A Quantum dot light emitting device and quantum dot layer patterning method 京东方科技集团股份有限公司 2023-11-28 — — CN disclosed
WO-2023178604-A1 QUANTUM DOT LIGHT-EMITTING DEVICE AND QUANTUM DOT LAYER PATTERNING METHOD 京东方科技集团股份有限公司 2023-09-28 — — WO disclosed
US-20210115489-A1 NOVEL MEDIATOR KIKKOMAN CORPORATION (JP) 2021-04-22 — — US disclosed
CN-108273478-B Formaldehyde removal composition and product 李怀玉 2021-03-02 — — CN disclosed
CN-108273478-A A kind of formaldehyde removing composition and product 李怀玉 2018-07-13 — — CN disclosed
US-9932300-B2 N,N′-diarylurea compounds and N,N′-diarylthiourea compounds as inhibitors of translation initiation PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2018-04-03 — — US disclosed
US-20160318857-A1 N,N'-Diarylurea Compounds and N,N'-Diarylthiourea Compounds as Inhibitors of Translation Initiation PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2016-11-03 — — US disclosed
US-9421211-B2 N,N′-diarylurea compounds and N,N′-diarylthiourea compounds as inhibitors of translation initiation PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2016-08-23 — — US disclosed
EP-1944332-B1 Method of modifying surface layer of molded resin NAT INST OF ADVANCED IND SCIEN (JP) 2012-08-08 — — EP disclosed
US-20120115915-A1 N,N'-DIARYLUREA COMPOUNDS AND N,N'-DIARYLTHIOUREA COMPOUNDS AS INHIBITORS OF TRANSLATION INITIATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2012-05-10 — — US disclosed
EP-1944332-A2 Modification method of surface layer of molded resin article, and modification apparatus of surface layer of molded resin article National Institute of Advanced Industrial Science and Technology (JP) 2008-07-16 — — EP disclosed
US-20060156986-A1 Modification method of surface layer of molded resin article, and modification apparatus of surface layer of molded resin article NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2006-07-20 — — US disclosed
US-7078072-B1 Method of modifying surface layer of molded resin and apparatus for modifying surface layer of molded resin NATIONAL INSTITUE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2006-07-18 — — US disclosed
US-7041332-B2 Modification method of surface layer of molded resin article, and modification apparatus of surface layer of molded resin article NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2006-05-09 — — US disclosed
US-20040195206-A1 Modification method of surface layer of molded resin article, and modification apparatus of surface layer of molded resin article NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2004-10-07 — — US disclosed
EP-1179558-A1 METHOD OF MODIFYING SURFACE LAYER OF MOLDED RESIN AND APPARATUS FOR MODIFYING SURFACE LAYER OF MOLDED RESIN Japan as represented by Secretary of Agency of Industrial Science and Technology (JP) 2002-02-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160318857-A1 N,N'-Diarylurea Compounds and N,N'-Diarylthiourea Compounds as Inhibitors of Translation Initiation NSUN2, EIF2AK2, RNGTT KMT2A 761/4885ALDH1A1 3464/4885MEN1 2936/4885
US-20210115489-A1 NOVEL MEDIATOR MPO, EPX, LPO KMT2A 3104/4885ALDH1A1 1833/4885MEN1 2351/4885
US-20120115915-A1 N,N'-DIARYLUREA COMPOUNDS AND N,N'-DIARYLTHIOUREA COMPOUNDS AS INHIBITORS OF TRANSLATION INITIATION NSUN2, EIF2AK2, RNGTT KMT2A 761/4885ALDH1A1 3464/4885MEN1 2936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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