SCHEMBL2684262

SCHEMBL2684262

CC[C@@H](C(N)=O)N1CCC(C(=O)O)C1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA3 P07451 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA13 Q8N1Q1 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
ACE P12821 2/20 0.39
DPP4 P27487 2/20 0.33
ITGB2 P05107 2/20 0.33
ICAM1 P05362 2/20 0.33
ITGAL P20701 2/20 0.33
PTPN1 P18031 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10078330 1.00 LMNA (0.50) LMNACA12CA1CA2CA3
SCHEMBL16093503 0.88 ACE (0.41) LMNACA12CA1CA2CA3
SCHEMBL4519294 0.84 LMNA (0.47) LMNACA12CA1CA2CA3
SCHEMBL12052203 0.81 LMNA (0.53) LMNACA12CA1CA2CA3
SCHEMBL10029734 0.81 TSHR (0.41) ACEDPP4PTPN1MAPT
SCHEMBL28241899 0.79 LMNA (0.51) LMNACA12CA1CA2CA3
SCHEMBL28241900 0.79 LMNA (0.51) LMNACA12CA1CA2CA3
SCHEMBL15190077 0.79 LMNA (0.48) LMNACA12CA1CA2CA3
SCHEMBL10078336 0.79 LMNA (0.48) LMNACA12CA1CA2CA3
SCHEMBL10078325 0.78 LMNA (0.50) LMNACA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1993998-B1 3-CARBOXY- 2-OXO-1 -PYRROLIDINE DERIVATIVES AND THEIR USES UCB PHARMA SA (BE) 2013-08-21 EP claimed
US-12203938-B2 Levetiracetam immunoassays ARK DIAGNOSTICS, INC. (US) 2025-01-21 US disclosed
US-20220357331-A1 Levetiracetam Immunoassays ARES CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT 2022-11-10 US disclosed
US-11231424-B2 Levetiracetam immunoassays ARK DIAGNOSTICS, INC. (US) 2022-01-25 US disclosed
US-20200240991-A1 Levetiracetam Immunoassays ARES CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT 2020-07-30 US disclosed
US-20150044693-A1 Levetiracetam Immunoassays ARK DIAGNOSTICS, INC. 2015-02-12 US disclosed
US-8841136-B2 Levetiracetam immunoassays ARK DIAGNOSTICS, INC. (US) 2014-09-23 US disclosed
EP-1993998-B1 3-CARBOXY- 2-OXO-1 -PYRROLIDINE DERIVATIVES AND THEIR USES UCB PHARMA SA (BE) 2013-08-21 EP disclosed
EP-2349335-B1 LEVETIRACETAM IMMUNOASSAYS ARK DIAGNOSTICS INC (US) 2013-08-07 EP disclosed
US-20120190047-A1 Levetiracetam Immunoassays ARES CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT 2012-07-26 US disclosed
US-8168756-B2 Levetiracetam immunoassays ARK DIAGNOSTICS, INC. (US) 2012-05-01 US disclosed
US-8076493-B2 3-carboxy-2-oxo-1-pyrrolidine derivatives and their uses UCB PHARMA, S.A. (BE) 2011-12-13 US disclosed
US-20100173427-A1 LEVETIRACETAM IMMUNOASSAYS ARES CAPITAL CORPORATION, AS ADMINISTRATIVE AGENT 2010-07-08 US disclosed
US-20090012313-A1 3-Carboxy-2-Oxo-1-Pyrrolidine Derivatives and Their Uses UCB PHARMA, S.A. (BE) 2009-01-08 US disclosed
EP-1993998-A1 3-CARBOXY- 2-OXO-1 -PYRROLIDINE DERIVATIVES AND THEIR USES UCB Pharma, S.A. (BE) 2008-11-26 EP disclosed
WO-2007065634-A1 3-CARBOXY- 2-OXO-1 -PYRROLIDINE DERIVATIVES AND THEIR USES UCB PHARMA, S.A. (BE) 2007-06-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12203938-B2 Levetiracetam immunoassays GABRG1, GABRA6, LY96 LMNA 1758/4885CA12 727/4885CA1 192/4885
US-20220357331-A1 Levetiracetam Immunoassays GABRG1, GABRA6, LY96 LMNA 1758/4885CA12 727/4885CA1 192/4885
US-20090012313-A1 3-Carboxy-2-Oxo-1-Pyrrolidine Derivatives and Their Uses ALDH18A1, PYCR1, OPRD1 LMNA 4658/4885CA12 1665/4885CA1 2436/4885
US-20200240991-A1 Levetiracetam Immunoassays GABRG1, GABRA6, LY96 LMNA 1758/4885CA12 727/4885CA1 192/4885
US-20120190047-A1 Levetiracetam Immunoassays GABRG1, GABRA6, LY96 LMNA 1758/4885CA12 727/4885CA1 192/4885
US-11231424-B2 Levetiracetam immunoassays GABRG1, GABRA6, LY96 LMNA 1758/4885CA12 727/4885CA1 192/4885
US-20100173427-A1 LEVETIRACETAM IMMUNOASSAYS GABRG1, GABRA6, LY96 LMNA 1758/4885CA12 727/4885CA1 192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.