Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.54 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 10/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL7125450 | 1.00 | LPAR3 (0.54) | LPAR3LPAR2TRPM8FAAHTSHR | |
| Potassium Ion SCHEMBL23037450 | 1.00 | LPAR3 (0.54) | LPAR3LPAR2TRPM8FAAHTSHR | |
| Potassium Ion SCHEMBL2544031 | 0.97 | LPAR3 (0.50) | LPAR3LPAR2TRPM8FAAH | |
| SCHEMBL23534093 | 0.95 | LPAR3 (0.54) | LPAR3LPAR2TRPM8FAAHTSHR | |
| SCHEMBL20985763 | 0.95 | LPAR3 (0.54) | LPAR3LPAR2TRPM8FAAHTSHR | |
| SCHEMBL20985742 | 0.95 | LPAR3 (0.54) | LPAR3LPAR2TRPM8FAAHTSHR | |
| SCHEMBL23534148 | 0.95 | LPAR3 (0.54) | LPAR3LPAR2TRPM8FAAHTSHR | |
| SCHEMBL23534083 | 0.95 | LPAR3 (0.54) | LPAR3LPAR2TRPM8FAAHTSHR | |
| SCHEMBL23534150 | 0.95 | LPAR3 (0.54) | LPAR3LPAR2TRPM8FAAHTSHR | |
| SCHEMBL23037447 | 0.95 | LPAR3 (0.54) | LPAR3LPAR2TRPM8FAAHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846978-B2 | Electronic devices comprising novel phosphonic acid surface modifiers | IMPERIAL INNOVATIONS LTD. (GB) | 2014-09-30 | — | — | US | disclosed |
| EP-2417142-B1 | ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS | GEORGIA TECH RES INST (US) | 2014-07-23 | — | — | EP | disclosed |
| US-8586208-B2 | Stable electrodes with modified work functions and methods for organic electronic devices | GEORGIA TECH RESEARCH CORPORATION (US) | 2013-11-19 | — | — | US | disclosed |
| US-20120114974-A1 | ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS | NATIONAL SCIENCE FOUNDATION | 2012-05-10 | — | — | US | disclosed |
| WO-2010115854-A1 | ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-10-14 | — | — | WO | disclosed |
| WO-2010007081-A1 | STABLE ELECTRODES WITH MODIFIED WORK FUNCTIONS AND METHODS FOR ORGANIC ELECTRONIC DEVICES | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120114974-A1 | ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS | EFNA1, PHOSPHO1, EPHA6 | LPAR3 635/4885LPAR2 560/4885TRPM8 3475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.