Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 5/20 | 0.46 |
| ▸ | ACE | P12821 | 4/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.46 |
| ▸ | CPA1 | P15085 | 2/20 | 0.42 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.42 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20849755 | 0.91 | MAPT (0.46) | ALDH1A1MAPTADAMTS5PTGS1 | |
| SCHEMBL20849762 | 0.91 | MAPT (0.46) | ALDH1A1MAPTADAMTS5PTGS1 | |
| SCHEMBL1706858 | 0.84 | ESR1 (0.42) | MAPTGAATAAR1 | |
| SCHEMBL20849763 | 0.82 | RIPK1 (0.42) | MMEACECPA1GAAHTT | |
| SCHEMBL1707342 | 0.82 | MAOB (0.55) | FFAR1PPARGPPARAPTGS1 | |
| SCHEMBL22872309 | 0.79 | CYP1A2 (0.48) | ALDH1A1MAPTCPA1SRRADAMTS5 | |
| SCHEMBL8910360 | 0.79 | MAPT (0.55) | ALDH1A1MAPTGAAPTGS1HTT | |
| SCHEMBL14519751 | 0.79 | MAPT (0.55) | ALDH1A1MAPTGAAPTGS1HTT | |
| SCHEMBL10197473 | 0.75 | ALDH1A1 (0.68) | ALDH1A1MAPTMMEACEACE2 | |
| SCHEMBL15085660 | 0.75 | ALDH1A1 (0.49) | ALDH1A1MAPTMMEACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382949-A1 | LINEAR APELIN RECEPTOR AGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2023-11-30 | — | — | US | disclosed |
| US-20230382949-A1 | LINEAR APELIN RECEPTOR AGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382949-A1 | LINEAR APELIN RECEPTOR AGONISTS | APLNR, MTNR1A, EDNRA | ALDH1A1 2876/4885MAPT 4403/4885MME 1551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.