SCHEMBL26915664

SCHEMBL26915664

COCCn1ccc(=O)[nH]c1=O

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.58
DUT P33316 11/20 0.54
CRBN Q96SW2 2/20 0.52
PKM P14618 1/20 0.50
PDE3A Q14432 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL29997761 0.92 L3MBTL1 (0.51) L3MBTL1DUTCRBNPKM
SCHEMBL25786392 0.89 DUT (0.62) L3MBTL1DUTCRBNPKMPDE3A
SCHEMBL7231374 0.85 PKM (0.53) L3MBTL1DUTCRBNPKM
SCHEMBL6425133 0.84 L3MBTL1 (0.43) L3MBTL1DUTCRBNPKM
SCHEMBL4348697 0.84 L3MBTL1 (0.59) L3MBTL1DUTCRBNPKM
SCHEMBL31592762 0.81 L3MBTL1 (0.58) L3MBTL1DUTCRBNPKMPDE3A
SCHEMBL4286089 0.81 PKM (0.57) L3MBTL1DUTCRBNPKM
SCHEMBL24066366 0.81 PKM (0.54) L3MBTL1DUTCRBNPKM
SCHEMBL14861415 0.79 L3MBTL1 (0.54) L3MBTL1DUTCRBNPKM
SCHEMBL6864606 0.78 DUT (0.57) L3MBTL1DUTCRBNPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240158412-A1 UBIQUITIN-SPECIFIC PROTEASE 7 (USP7) INHIBITORS AND USES THEREOF FAXIAN THERAPEUTICS, LLC 2024-05-16 US disclosed
EP-4288442-A1 UBIQUITIN-SPECIFIC PROTEASE 7 (USP7) INHIBITORS AND USES THEREOF Faxian Therapeutics, LLC (US) 2023-12-13 EP disclosed
WO-2022170198-A1 UBIQUITIN-SPECIFIC PROTEASE 7 (USP7) INHIBITORS AND USES THEREOF FAXIAN THERAPEUTICS, LLC (US) 2022-08-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240158412-A1 UBIQUITIN-SPECIFIC PROTEASE 7 (USP7) INHIBITORS AND USES THEREOF USP7, USP28, USP1 L3MBTL1 355/4885DUT 1520/4885CRBN 276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.