Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.67 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.67 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.62 |
| ▸ | CTSL | P07711 | 1/20 | 0.60 |
| ▸ | CTSS | P25774 | 1/20 | 0.60 |
| ▸ | TGM2 | P21980 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.58 |
| ▸ | ITGAV | P06756 | 2/20 | 0.58 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.57 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.55 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.55 |
| ▸ | CPB1 | P15086 | 1/20 | 0.55 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL209612 | 0.97 | SIRT2 (0.71) | SIRT2SIRT1FOLH1CTSLCTSS | |
| SCHEMBL4173691 | 0.91 | FOLH1 (0.72) | SIRT2SIRT1FOLH1TGM2ITGB3 | |
| SCHEMBL11875673 | 0.91 | FOLH1 (0.72) | SIRT2SIRT1FOLH1TGM2ITGB3 | |
| SCHEMBL4173693 | 0.91 | FOLH1 (0.72) | SIRT2SIRT1FOLH1TGM2ITGB3 | |
| SCHEMBL14357907 | 0.89 | SIRT2 (0.72) | SIRT2SIRT1FOLH1CTSLCTSS | |
| SCHEMBL806151 | 0.87 | FOLH1 (0.78) | SIRT2SIRT1FOLH1TGM2ITGB3 | |
| SCHEMBL464715 | 0.87 | FOLH1 (0.78) | SIRT2SIRT1FOLH1TGM2ITGB3 | |
| SCHEMBL4561005 | 0.87 | FOLH1 (0.78) | SIRT2SIRT1FOLH1TGM2ITGB3 | |
| SCHEMBL4126228 | 0.87 | CTSL (0.72) | SIRT2SIRT1FOLH1CTSLCTSS | |
| SCHEMBL11332452 | 0.87 | CTSL (0.72) | SIRT2SIRT1FOLH1CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173133-B2 | Acyl pseudodipeptides which carry a functionalized auxiliary arm | OM PHARMA (CH) | 2012-05-08 | — | — | US | disclosed |
| US-7799762-B2 | Acyl pseudodipeptides which carry a functionalised auxialiary arm | OM PHARMA (CH) | 2010-09-21 | — | — | US | disclosed |
| US-20100215685-A1 | ACYL PSEUDODIPEPTIDES WHICH CARRY A FUNCTIONALIZED AUXILIARY ARM | OM PHARMA (CH) | 2010-08-26 | — | — | US | disclosed |
| US-7157092-B1 | Acyl pseudodipeptides, preparation method and pharmaceutical compositions containing same | OM PHARMA (CH) | 2007-01-02 | — | — | US | disclosed |
| US-20060148678-A1 | Novel acyl-dipeptide-like compounds, a method for preparing the same and pharmaceutical compositions containing such products | OM PHARMA | 2006-07-06 | — | — | US | disclosed |
| US-20050192232-A1 | Novel acyl-dipeptide-like compounds bearing an accessory functional side chain spacer, a method for preparing the same and pharmaceutical compositions containing such products | OM PHARMA (CH) | 2005-09-01 | — | — | US | disclosed |
| US-20030203852-A1 | Acyl pseudodipeptides which carry a functionalised auxialiary arm | OM PHARMA (CH) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192232-A1 | Novel acyl-dipeptide-like compounds bearing an accessory functional side chain spacer, a method for preparing the same and pharmaceutical compositions containing such products | PIGS, AADAT, CD74 | SIRT2 2044/4885SIRT1 3319/4885FOLH1 460/4885 |
| US-20060148678-A1 | Novel acyl-dipeptide-like compounds, a method for preparing the same and pharmaceutical compositions containing such products | PTMS, DNPEP, QPCT | SIRT2 3137/4885SIRT1 3084/4885FOLH1 412/4885 |
| US-20030203852-A1 | Acyl pseudodipeptides which carry a functionalised auxialiary arm | PIGS, AADAC, ENPP2 | SIRT2 1815/4885SIRT1 3539/4885FOLH1 825/4885 |
| US-20100215685-A1 | ACYL PSEUDODIPEPTIDES WHICH CARRY A FUNCTIONALIZED AUXILIARY ARM | PIGS, DNPEP, ENPP2 | SIRT2 2392/4885SIRT1 3914/4885FOLH1 900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.