Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 3/20 | 0.52 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | WNT3A | P56704 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31716601 | 0.86 | WNT3A (0.59) | NPC1RAB9ASMN1; SMN2PKMHPGD | |
| SCHEMBL13791195 | 0.79 | HSP90AB1 (0.54) | HSD17B1HSD17B2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27694530 | 0.78 | RAB9A (0.49) | NPC1RAB9ASMN1; SMN2PKMHPGD | |
| SCHEMBL21228142 | 0.77 | HSD17B1 (0.56) | HSD17B1HSD17B2KDM1AFYN | |
| SCHEMBL29914699 | 0.77 | HSD17B1 (0.56) | HSD17B1HSD17B2KDM1AFYN | |
| SCHEMBL30435086 | 0.75 | HSP90AB1 (0.67) | SMN1; SMN2PKMHPGDNFKB1ALDH1A1 | |
| SCHEMBL979023 | 0.75 | HSP90AB1 (0.67) | SMN1; SMN2PKMHPGDNFKB1ALDH1A1 | |
| SCHEMBL20799456 | 0.74 | HSD17B1 (0.56) | HSD17B1HSD17B2LMNAKDM1AFYN | |
| SCHEMBL30452574 | 0.74 | CYP11B1 (0.51) | NPC1RAB9AALDH1A1 | |
| SCHEMBL28440183 | 0.74 | CYP11B1 (0.51) | NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858918-B2 | GLP-1R modulating compounds | GILEAD SCIENCES, INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-11858918-B2 | GLP-1R modulating compounds | GILEAD SCIENCES, INC. (US) | 2024-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858918-B2 | GLP-1R modulating compounds | GLP1R, GIPR, GPR119 | HSD17B1 1910/4885HSD17B2 2411/4885NPC1 1188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.