Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19707556 | 0.94 | RAB9A (0.61) | PTPN1NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL27676491 | 0.84 | RHOC (0.53) | PTPN1NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL593746 | 0.82 | AKR1C3 (0.73) | PTPN1NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL6201893 | 0.81 | ALDH1A1 (0.59) | PTPN1NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL22130998 | 0.81 | PTPN1 (0.71) | PTPN1NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL23014264 | 0.81 | PTPN1 (0.57) | PTPN1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL28512358 | 0.80 | RAB9A (0.61) | PTPN1NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL8987260 | 0.79 | NPC1 (0.59) | PTPN1NPC1RAB9AALDH1A1HSD11B1 | |
| SCHEMBL9407545 | 0.79 | HDAC4 (0.62) | NPC1RAB9AHTTL3MBTL1LMNA | |
| SCHEMBL9768118 | 0.79 | P2RX1 (0.49) | PTPN1NPC1RAB9AGSK3BMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002350-A1 | PROTEIN AND LIPID THERAPEUTIC TARGETS | UNIV PITTSBURGH COMMONWEALTH SYS HIGHER EDUCATION (US) | 2024-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240002350-A1 | PROTEIN AND LIPID THERAPEUTIC TARGETS | PEBP1, ALOX15, ALOX15B | PTPN1 4392/4885NPC1 1408/4885RAB9A 2624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.