Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11499443 | 0.87 | — | — | |
| SCHEMBL910733 | 0.85 | — | — | |
| SCHEMBL12711853 | 0.81 | ZDHHC20 (0.46) | ALDH1A1TSHRZDHHC20ZDHHC2 | |
| SCHEMBL28338426 | 0.79 | ZDHHC20 (0.53) | TSHRZDHHC20ZDHHC2 | |
| SCHEMBL676588 | 0.78 | — | — | |
| SCHEMBL1290917 | 0.78 | — | — | |
| SCHEMBL820189 | 0.76 | LMNA (0.36) | LMNATSHRTDP1 | |
| SCHEMBL28907228 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL7803046 | 0.75 | ACHE (0.36) | LMNATSHRZDHHC20ZDHHC2 | |
| SCHEMBL3888299 | 0.74 | TSHR (0.40) | ALDH1A1TSHRZDHHC20ZDHHC2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 449 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728339-B1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | AMO Ireland (IE) | 2022-07-06 | — | — | EP | claimed |
| US-11359031-B2 | Composition for ophthalmological products | Johnson & Johnson Surgical Vision, Inc. (US) | 2022-06-14 | — | — | US | claimed |
| EP-3200840-B1 | LOW-WATER CONTENT ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES | ALCON INC (CH) | 2021-11-17 | — | — | EP | claimed |
| EP-3728339-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2020-10-28 | — | — | EP | claimed |
| US-20200332041-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | MERCK PATENT GMBH (DE) | 2020-10-22 | — | — | US | claimed |
| EP-3200839-B1 | HYDROPHOBIC ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES | NOVARTIS AG (CH) | 2019-09-04 | — | — | EP | claimed |
| EP-3502147-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2019-06-26 | — | — | EP | claimed |
| US-20180346629-A1 | Biocompatible polymers and co-polymers, and uses thereof | GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2018-12-06 | — | — | US | claimed |
| EP-3223870-B1 | WET-PACK INTRAOCULAR LENS MATERIALS WITH HIGH REFRACTIVE INDEX | NOVARTIS AG (CH) | 2018-09-26 | — | — | EP | claimed |
| US-10064977-B2 | Wet-pack intraocular lens materials with high refractive index | NOVARTIS AG (CH) | 2018-09-04 | — | — | US | claimed |
| US-6551684-B1 | Substrate with interstitial gaps having polymeric membrane within the gaps that are thinner than the cross-sectional thickness of the substrate | GRADIPORE LIMITED (AU) | 2003-04-22 | — | — | US | claimed |
| WO-2002013956-A1 | MEMBRANES AND METHOD OF MANUFACTURE THEREOF | GRADIPORE LIMITED (AU) | 2002-02-21 | — | — | WO | claimed |
| EP-0425436-B1 | Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof | CIBA GEIGY AG (CH) | 1996-12-27 | — | — | EP | claimed |
| EP-0421264-B1 | Hydrophilic swellable polymers | CASSELLA FARBWERKE MAINKUR AG (DE) | 1994-08-10 | — | — | EP | claimed |
| US-5236965-A | Absorbers, acrylic | CASSELLA AKTIENGESELLSCHAFT (DE) | 1993-08-17 | — | — | US | claimed |
| US-5214075-A | Used as absorption agents for water and aqueous solutions | CASSELLA AKTIENGESELLSCHAFT (DE) | 1993-05-25 | — | — | US | claimed |
| US-5182312-A | Crosslinked acrylic polymer foams | CASSELLA AKTIENGESELLSCHAFT (DE) | 1993-01-26 | — | — | US | claimed |
| US-5079319-A | Contact Lenses | CIBA-GEIGY CORPORATION (US) | 1992-01-07 | — | — | US | claimed |
| EP-0425436-A2 | Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof | CIBA-GEIGY AG (CH) | 1991-05-02 | — | — | EP | claimed |
| US-4539200-A | CLEANING WOUNDS CROSSLINKED POLYAMIDES | THE KENDALL COMPANY (US) | 1985-09-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180346629-A1 | Biocompatible polymers and co-polymers, and uses thereof | ARG1, CRYAA, COL1A1 | LMNA 343/4885ALDH1A1 2924/4885TSHR 4182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.