SCHEMBL2706930

SCHEMBL2706930

O=[N+]([O-])c1cc(C2(c3ccc(O)c([N+](=O)[O-])c3)c3ccccc3-c3ccccc32)ccc1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.56
ESR2 Q92731 1/20 0.56
MAPK1 P28482 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
GPR35 Q9HC97 2/20 0.47
ALDH1A1 P00352 2/20 0.47
TP53 P04637 2/20 0.47
HPGD P15428 1/20 0.47
TSHR P16473 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
HSD17B10 Q99714 2/20 0.46
ALOX15 P16050 1/20 0.46
MAPT P10636 5/20 0.44
POLB P06746 1/20 0.44
APEX1 P27695 1/20 0.44
CASP6 P55212 1/20 0.44
ALDH5A1 P51649 1/20 0.44
ABAT P80404 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17443143 0.83 MAPK1 (0.44) ESR1ESR2MAPK1SMN1; SMN2GPR35
SCHEMBL2708570 0.81 MAPK1 (0.44) ESR1ESR2MAPK1SMN1; SMN2GPR35
SCHEMBL2709865 0.81 HNF4A (0.41) ESR1ESR2MAPK1SMN1; SMN2GPR35
SCHEMBL4959116 0.79 LMNA (0.64) ESR1ESR2SMN1; SMN2ALDH1A1TP53
SCHEMBL29375514 0.77 ESR1 (0.71) ESR1ESR2SMN1; SMN2ALDH1A1TP53
SCHEMBL1324119 0.77 ESR1 (0.71) ESR1ESR2SMN1; SMN2ALDH1A1TP53
SCHEMBL2710257 0.76 MEN1 (0.50) MAPK1SMN1; SMN2GPR35ALDH1A1TP53
SCHEMBL19084236 0.73 ALDH1A1 (0.42) ESR1ESR2MAPK1SMN1; SMN2ALDH1A1
SCHEMBL19084232 0.73 ALDH1A1 (0.61) MAPK1SMN1; SMN2GPR35ALDH1A1TP53
SCHEMBL16800913 0.73 ALDH1A1 (0.62) SMN1; SMN2ALDH1A1TSHRL3MBTL1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024085030-A1 METHOD FOR PRODUCING SEMICONDUCTOR SUBSTRATE AND COMPOSITION JSR株式会社 2024-04-25 WO disclosed
US-8337982-B2 Comprising first repeating unit obtained by reaction of bisaminophenol compound and dicarboxylic acid, at least one of which has diamondoid structure and second repeating unit obtained by reaction of bisaminophenol compound having no diamondoid structure and dicarboxylic acid; heat resistance SUMITOMO BAKELITE CO., LTD. (JP) 2012-12-25 US disclosed
EP-2000510-B1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM SUMITOMO BAKELITE CO (JP) 2012-05-02 EP disclosed
US-7863347-B2 Resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2011-01-04 US disclosed
US-20090118431-A1 RESIN COMPOSITION, VARNISH, RESIN FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE COMPANY, LTD (JP) 2009-05-07 US disclosed
EP-2000510-A1 RESIN COMPOSITION, VARNISH, RESIN FILM, AND SEMICONDUCTOR DEVICE USING THE RESIN FILM Sumitomo Bakelite Company, Ltd. (JP) 2008-12-10 EP disclosed
US-20080206548-A1 Benzoxazole Resin Precursor, Polybenzoxazole Resin, Resin Film And Semiconductor Device SUMITOMO BAKELITE CO., LTD (JP) 2008-08-28 US disclosed
JP-2007291058-A FLUORENE DERIVATIVE AND METHOD FOR PRODUCING THE SAME SUMITOMO BAKELITE CO LTD 2007-11-08 JP disclosed
EP-1832619-A1 BENZOXAZOLE RESIN PRECURSOR, POLYBENZOXAZOLE RESIN, RESIN FILM, AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Company, Limited (JP) 2007-09-12 EP disclosed
US-7125814-B2 Bis-o-nitrophenols derivatives and poly-o-hydroxyamides, polybenzoxazoles, materials, and microelectronic devices made therefrom INFINEON TECHNOLOGIES AG (DE) 2006-10-24 US disclosed
US-20030100698-A1 Bis-o-nitrophenols derivatives and poly-o-hydroxyamides, polybenzoxazoles, materials, and microelectronic devices made therefrom POLARIS INNOVATIONS LIMITED (IE) 2003-05-29 US disclosed
JP-2002173470-A 9,9-BIS(3-NITRO-4-HYDROXYPHENYL)FLUORENE AND METHOD FOR PRODUCING THE SAME NIPPON KAYAKU CO LTD 2002-06-21 JP disclosed
JP-2002105034-A METHOD FOR PRODUCING 9,9-BIS(3-AMINO-4-HYDROXYPHENYL) FLUORENE NIPPON KAYAKU CO LTD 2002-04-10 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030100698-A1 Bis-o-nitrophenols derivatives and poly-o-hydroxyamides, polybenzoxazoles, materials, and microelectronic devices made therefrom FHIT, NONO, TET3 ESR1 1135/4885ESR2 2053/4885MAPK1 3849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.