Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 6/20 | 0.53 |
| ▸ | WNT3 | P56703 | 2/20 | 0.53 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | BRD2 | P25440 | 2/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27034291 | 0.82 | KMT2A (0.42) | SFRP1WNT3HDAC4ALDH1A1TSHR | |
| SCHEMBL27070111 | 0.78 | SFRP1 (0.39) | SFRP1WNT3 | |
| SCHEMBL27070114 | 0.77 | SFRP1 (0.56) | SFRP1WNT3BRD4HDAC4CCR8 | |
| SCHEMBL24529785 | 0.74 | WNT3 (0.54) | SFRP1WNT3HDAC4ALDH1A1CYP3A4 | |
| SCHEMBL26065736 | 0.73 | ALDH1A1 (0.48) | BRD4BRD2BRD3ALDH1A1CYP3A4 | |
| SCHEMBL27034226 | 0.72 | PTGS2 (0.36) | SFRP1WNT3BRD4HDAC4 | |
| SCHEMBL14538236 | 0.72 | ALDH1A1 (0.71) | ALDH1A1CYP3A4TSHRKDM4ERECQL | |
| SCHEMBL4616410 | 0.72 | SFRP1 (0.68) | SFRP1WNT3CCR8ALDH1A1 | |
| SCHEMBL4733987 | 0.72 | SFRP1 (0.58) | SFRP1WNT3BRD4BRD2BRD3 | |
| SCHEMBL12061693 | 0.72 | KMT2A (0.62) | SFRP1WNT3ALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024020156-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-01-25 | — | — | WO | disclosed |