SCHEMBL27093335

SCHEMBL27093335

CO[C@@H]1[C@@H](O)[C@@H](CO)O[C@H]1n1cc(C(=O)NCc2ccc3c(c2)OCO3)c(=O)[nH]c1=O

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ PKM P14618 2/20 0.46
▸ USP2 O75604 1/20 0.46
▸ HPGD P15428 7/20 0.45
▸ ALDH1A1 P00352 5/20 0.44
▸ POLB P06746 2/20 0.44
▸ LMNA P02545 1/20 0.44
▸ MCL1 Q07820 1/20 0.44
▸ HKDC1 Q2TB90 1/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ CNR1 P21554 1/20 0.43
▸ CNR2 P34972 1/20 0.43
▸ TK2 O00142 1/20 0.43
▸ MEN1 O00255 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ MAPT P10636 1/20 0.42
▸ GAA P10253 1/20 0.42
▸ TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29125193 0.92 KDM4E (0.46) PKMUSP2HPGDALDH1A1POLB
SCHEMBL19834971 0.86 TK2 (0.48) TK2
SCHEMBL27094652 0.85 TK2 (0.46) TK2
SCHEMBL10101281 0.85 TK2 (0.53) ALDH1A1KDM4ETK2
SCHEMBL29163657 0.85 TK2 (0.53) ALDH1A1KDM4ETK2
SCHEMBL10104844 0.85 TK2 (0.53) ALDH1A1KDM4ETK2
SCHEMBL27093309 0.84 TK2 (0.48) TK2
SCHEMBL27094653 0.83 TK2 (0.48) ALDH1A1KDM4ETK2
SCHEMBL27093412 0.83 TK2 (0.49) TK2
SCHEMBL22208063 0.81 TK1 (0.51) LMNAKDM4ETK2SMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218374-A1 Nucleic Acid Compounds That Bind Coronavirus Proteins SOMALOGIC OPERATING CO., INC. (US) 2024-07-04 — — US disclosed
EP-4323374-A1 MODIFIED NUCLEOSIDES SomaLogic Operating Co., Inc. (US) 2024-02-21 — — EP disclosed
CN-117242085-A Modified nucleosides 私募蛋白质体操作有限公司 2023-12-15 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240218374-A1 Nucleic Acid Compounds That Bind Coronavirus Proteins SARS1, RNGTT, PABPC1 PKM 3531/4885USP2 2229/4885HPGD 4643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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