Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27100872 | 0.79 | MEN1 (0.34) | LMNAPOLB | |
| SCHEMBL26222036 | 0.78 | SLC6A2 (0.34) | LMNAPOLB | |
| SCHEMBL19190082 | 0.76 | MEN1 (0.39) | LMNA | |
| SCHEMBL27100885 | 0.75 | SLC6A2 (0.35) | LMNA | |
| SCHEMBL28042989 | 0.72 | MEN1 (0.40) | LMNA | |
| Phosphonic Acid SCHEMBL28952677 | 0.70 | MEN1 (0.35) | LMNA | |
| SCHEMBL26222032 | 0.68 | CHRM2 (0.36) | LMNAPOLB | |
| SCHEMBL27898432 | 0.67 | MEN1 (0.37) | LMNA | |
| SCHEMBL1582351 | 0.66 | MEN1 (0.39) | LMNA | |
| SCHEMBL19190077 | 0.66 | LMNA (0.39) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912800-B2 | Amide-functionalized polymerization initiators and their use in the manufacture of ophthalmic lenses | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2024-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912800-B2 | Amide-functionalized polymerization initiators and their use in the manufacture of ophthalmic lenses | CRYAA, UACA, CRYAB | MTNR1A 2199/4885MTNR1B 2386/4885TACR1 1944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.