Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26222036 | 0.89 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL27100872 | 0.81 | MEN1 (0.34) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL27100868 | 0.75 | MTNR1A (0.41) | LMNA | |
| SCHEMBL19190082 | 0.73 | MEN1 (0.39) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL26222043 | 0.73 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL28042989 | 0.69 | MEN1 (0.40) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| Phosphonic Acid SCHEMBL28952677 | 0.68 | MEN1 (0.35) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL19190077 | 0.66 | LMNA (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL26222032 | 0.66 | CHRM2 (0.36) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27898432 | 0.65 | MEN1 (0.37) | SLC6A2SLC6A4SLC6A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912800-B2 | Amide-functionalized polymerization initiators and their use in the manufacture of ophthalmic lenses | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2024-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912800-B2 | Amide-functionalized polymerization initiators and their use in the manufacture of ophthalmic lenses | CRYAA, UACA, CRYAB | SLC6A2 4854/4885SLC6A4 4801/4885SLC6A3 4839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.