SCHEMBL27114131

SCHEMBL27114131

N=C(N)NCc1cccc(N2CCN(S)CC2)c1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ ITGB3 P05106 2/20 0.46
▸ ITGA2B P08514 2/20 0.46
▸ PRMT6 Q96LA8 1/20 0.46
▸ MEN1 O00255 3/20 0.43
▸ KMT2A Q03164 3/20 0.43
▸ LMNA P02545 3/20 0.43
▸ POLB P06746 2/20 0.43
▸ HTT P42858 2/20 0.43
▸ MAPT P10636 1/20 0.43
▸ AGXT P21549 3/20 0.41
▸ GFER P55789 1/20 0.40
▸ DRD2 P14416 1/20 0.38
▸ DRD3 P35462 1/20 0.38
▸ AOC3 Q16853 2/20 0.38
▸ RECQL P46063 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ KLKB1 P03952 1/20 0.37
▸ KLK1 P06870 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27113249 0.86 AGXT (0.57) ITGB3ITGA2BPRMT6MEN1KMT2A
SCHEMBL27113244 0.84 HTR7 (0.49) ITGB3ITGA2BPRMT6HTTMAPT
SCHEMBL27118870 0.83 PRMT6 (0.46) ITGB3ITGA2BPRMT6MEN1KMT2A
SCHEMBL27120294 0.83 PRMT6 (0.46) ITGB3ITGA2BPRMT6MEN1KMT2A
SCHEMBL27113417 0.83 PRMT6 (0.46) ITGB3ITGA2BPRMT6MEN1KMT2A
SCHEMBL27113243 0.82 PRMT6 (0.47) ITGB3ITGA2BPRMT6MEN1KMT2A
SCHEMBL27114252 0.80 PRMT6 (0.43) ITGB3ITGA2BPRMT6MEN1KMT2A
SCHEMBL27113245 0.77 SMN1; SMN2 (0.53) ITGB3ITGA2BMEN1KMT2ALMNA
SCHEMBL27114133 0.76 ITGB3 (0.43) ITGB3ITGA2BMEN1KMT2ALMNA
SCHEMBL17894400 0.73 MAOA (0.46) LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066135-A1 DRUG CONJUGATES AND USES THEREOF SUPERTRANS MEDICAL LTD (IL) 2024-02-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240066135-A1 DRUG CONJUGATES AND USES THEREOF SLC7A1, ABCB11, SLC1A5 ITGB3 475/4885ITGA2B 1099/4885PRMT6 1447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback