Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1C | P00326 | 3/20 | 0.48 |
| ▸ | ADH1A | P07327 | 3/20 | 0.48 |
| ▸ | ADH4 | P08319 | 3/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ADH1B | P00325 | 2/20 | 0.39 |
| ▸ | ADH7 | P40394 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9659079 | 1.00 | ADH1C (0.48) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL9661153 | 1.00 | ADH1C (0.48) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL9660655 | 1.00 | ADH1C (0.48) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL9661741 | 1.00 | ADH1C (0.48) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL9658810 | 1.00 | ADH1C (0.48) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL9660670 | 1.00 | ADH1C (0.48) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL9660185 | 1.00 | ADH1C (0.48) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL271369 | 0.98 | ADH1A (0.45) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL3962903 | 0.95 | ADH1C (0.52) | ADH1CADH1AADH4DNM1TSHR | |
| SCHEMBL5175186 | 0.95 | ADH1C (0.52) | ADH1CADH1AADH4DNM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635307-B1 | PHARMACEUTICAL COMPOSITIONS | MELINTA SUBSIDIARY CORP (US) | 2020-07-29 | — | — | EP | disclosed |
| EP-1697309-B1 | BENZOYL-SUBSTITUTED PHENYLALANINE AMIDES | BASF SE (DE) | 2014-04-23 | — | — | EP | disclosed |
| EP-1888509-B1 | BENZOYL-SUBSTITUTED SERINE AMIDES | BASF SE (DE) | 2013-05-15 | — | — | EP | disclosed |
| US-8133851-B2 | Heteroaroyl-substituted serine amides | BASF SE (DE) | 2012-03-13 | — | — | US | disclosed |
| US-20110318470-A1 | Method For Improving Plant Health | BASF SE (DE) | 2011-12-29 | — | — | US | disclosed |
| US-20110209253-A1 | Method for Improving Plant Health | BASF SE (DE) | 2011-08-25 | — | — | US | disclosed |
| US-7879761-B2 | Herbicides; 1-{Methylcarbamoyl-[(1-methyl-3-trifluoromethyl-1H-pyrazol-4-carbonyl)amino]methyl}-allyl acetate; acylation of keto compounds and reduction of the ketone, or the serine derivative is reacted with a heteroaryl acid and then with a secondary or tertiary amine | BASF AKTIENGESELLSCHAFT (DE) | 2011-02-01 | — | — | US | disclosed |
| EP-2121583-B1 | HETEROARYL-SUBSTITUTED SERINE AMIDES | BASF SE (DE) | 2010-09-22 | — | — | EP | disclosed |
| US-7786046-B2 | Benzoyl-substituted serineamides | BASF AKTIENGESELLSCHAFT (DE) | 2010-08-31 | — | — | US | disclosed |
| US-20100099568-A1 | Heteroaroyl-Substituted Serine Amides | BASF SE (DE) | 2010-04-22 | — | — | US | disclosed |
| US-5888972-A | ENDOTHELIN ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-03-30 | — | — | US | disclosed |
| WO-1998031682-A1 | 4-(3-HETEROCYCLYL-1-BENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-07-23 | — | — | WO | disclosed |
| EP-0457195-B1 | Peptides having endothelin antagonist activity, a process for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-04-15 | — | — | EP | disclosed |
| US-5656604-A | HYPOTENSIVE AGENT; ENDOTHELIN ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| EP-0706532-A1 | NEW COMPOUND AND ITS PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-17 | — | — | EP | disclosed |
| US-5430022-A | Endothelin antagonists; hypotensive agents; treatment for angina pectoris, brain disorders, asthma, renal failure | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-04 | — | — | US | disclosed |
| WO-1995000537-A1 | NEW COMPOUND AND ITS PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-01-05 | — | — | WO | disclosed |
| US-5284828-A | Hypotensive agents | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 1994-02-08 | — | — | US | disclosed |
| EP-0517262-A1 | Trifluorothymidine derivatives, process for producing the same and anti-cancer agent containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-12-09 | — | — | EP | disclosed |
| EP-0457195-A2 | Peptides having endothelin antagonist activity, a process for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110318470-A1 | Method For Improving Plant Health | BROX, PAH, GUSB | ADH1C 785/4885ADH1A 833/4885ADH4 217/4885 |
| US-20100099568-A1 | Heteroaroyl-Substituted Serine Amides | SRM, ASNS, SRR | ADH1C 2544/4885ADH1A 1960/4885ADH4 1279/4885 |
| US-20110209253-A1 | Method for Improving Plant Health | AADAT, AAAS, GUSB | ADH1C 1322/4885ADH1A 1253/4885ADH4 499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.