Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15598396 | 0.89 | MGAM (0.39) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL17376202 | 0.88 | GAA (0.46) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL27654778 | 0.86 | MGAM (0.43) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL9686224 | 0.83 | HCAR2 (0.38) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL4685380 | 0.83 | ALDH1A1 (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL15581613 | 0.82 | MGAM (0.43) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL1495985 | 0.80 | ALDH1A1 (0.42) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL7840946 | 0.80 | MGAM (0.41) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL6160354 | 0.80 | L3MBTL1 (0.50) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL3841717 | 0.79 | L3MBTL1 (0.49) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620977-A | Synthesis method of thiazolidine pyrimidone acetic acid | 江苏弘和药物研发有限公司 | 2021-11-09 | — | — | CN | claimed |
| US-20250304571-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2025-10-02 | — | — | US | disclosed |
| EP-4565588-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | Suzhou Keen Therapeutics Co., Ltd. (CN) | 2025-06-11 | — | — | EP | disclosed |
| CN-113620977-B | Synthesis method of thiazolopyrimidinone acetic acid | 江苏弘和药物研发有限公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2023241620-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2023-12-21 | — | — | WO | disclosed |
| US-20230065740-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | SPV THERAPEUTICS INC. | 2023-03-02 | — | — | US | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-113620977-A | Synthesis method of thiazolidine pyrimidone acetic acid | 江苏弘和药物研发有限公司 | 2021-11-09 | — | — | CN | disclosed |
| EP-2675793-B1 | FAK INHIBITORS | CANCER THERAPEUTICS CRC PTY LTD (AU) | 2018-08-08 | — | — | EP | disclosed |
| US-20160367557-A1 | HETEROCYCLIC PYRIMIDINE CARBONIC ACID DERIVATIVES WHICH ARE USEFUL IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE | SAVIRA PHARMACEUTICALS GMBH | 2016-12-22 | — | — | US | disclosed |
| US-5155103-A | Methods of using new thieno-triazole-1,4-diazepino-2-carboxylic acid amides | BOEHRINGER INGELHEIM GMBH (DE) | 1992-10-13 | — | — | US | disclosed |
| US-5116971-A | Platelt-activating-factor antagonist | BOEHRINGER INGELHEIM KG (DE) | 1992-05-26 | — | — | US | disclosed |
| EP-0188094-B1 | QUINAZOLINE DERIVATIVES AND ANTIHYPERTENSIVE PREPARATIONS CONTAINING SAME AS EFFECTIVE COMPONENTS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-5082839-A | Platelet activating factor antagonist | BOEHRINGER INGELHEIM GMBH (DE) | 1992-01-21 | — | — | US | disclosed |
| US-4968794-A | ANTAGONISTS OF PLATELET ACTIVATING FACTOR | BOEHRINGER INGELHEIM KG (DE) | 1990-11-06 | — | — | US | disclosed |
| US-4734418-A | Quinazoline compounds and antihypertensives | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-03-29 | — | — | US | disclosed |
| EP-0188094-A2 | Quinazoline derivatives and antihypertensive preparations containing same as effective components | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1986-07-23 | — | — | EP | disclosed |
| US-4190657-A | ANTI-ANOXIA AND PSYCHOTROPIC ACTIVITY | SYNTHELABO (FR) | 1980-02-26 | — | — | US | disclosed |
| US-4089858-A | Heterocyclic-amino-acrylic acid derivatives | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1978-05-16 | — | — | US | disclosed |
| US-4024159-A | Process for the production of liquid acetals | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230065740-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | CDK2, CDK1, CCNK | MGAM 3918/4885GAA 3009/4885SI 4264/4885 |
| US-20250304571-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | VHL, BRCA1, TERT | MGAM 1969/4885GAA 84/4885SI 945/4885 |
| US-20160367557-A1 | HETEROCYCLIC PYRIMIDINE CARBONIC ACID DERIVATIVES WHICH ARE USEFUL IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE | ALAD, XDH, UACA | MGAM 2737/4885GAA 125/4885SI 1099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.