Acetic Acid

Acetic Acid

SCHEMBL27199849

CC(=O)O.Cc1cnc(C)c([C@@H]2CCCN2C)c1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CHRNB4 known ✓ P30926 1/20 0.40
CHRNA3 known ✓ P32297 1/20 0.40
AADAT Q8N5Z0 1/20 0.42
KDM4E B2RXH2 1/20 0.41
BLM P54132 1/20 0.41
ALOX15 P16050 1/20 0.41
CHRNB2 P17787 1/20 0.40
CHRNA7 P36544 1/20 0.40
CHRNA4 P43681 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31019632 0.91 CHRNB2 (0.46) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL30866557 0.91 CHRNB2 (0.46) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL9195587 0.91 CHRNB2 (0.46) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL27199840 0.91 CHRNB2 (0.46) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL10663646 0.90 CHRNB2 (0.45) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL10663642 0.90 CHRNB2 (0.45) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
Cadaverine Tartrate SCHEMBL30866577 0.90 BLM (0.54) AADATKDM4EBLMALOX15
Lactic Acid SCHEMBL27199943 0.90 BLM (0.46) AADATKDM4EBLMALOX15
L-Lactic Acid SCHEMBL27199946 0.90 BLM (0.46) AADATKDM4EBLMALOX15
Levulinic Acid SCHEMBL27199845 0.89 AADAT (0.38) AADATKDM4EBLMALOX15CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4683527-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2026-01-28 EP disclosed
US-20250289796-A1 COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2025-09-18 US disclosed
US-12358888-B2 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2025-07-15 US disclosed
US-12358889-B2 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2025-07-15 US disclosed
CN-118984653-A Vaporizable alkaloid compositions and methods of use thereof 瑞迪美天然有限公司 2024-11-19 CN disclosed
WO-2024155297-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2024-07-25 WO disclosed
US-20240246930-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2024-07-25 US disclosed
US-11964958-B1 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2024-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240246930-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF SRM, SCLY, SMOX CHRNB4 55/4885CHRNA3 116/4885AADAT 1957/4885
US-11964958-B1 Vaporizable alkaloid compositions and methods of use thereof SRM, SCLY, SMOX CHRNB4 55/4885CHRNA3 116/4885AADAT 1957/4885
US-20250289796-A1 COMPOSITIONS AND METHODS OF USE THEREOF OR10J3, TRPA1, TAS2R3 CHRNB4 205/4885CHRNA3 173/4885AADAT 1507/4885
US-12358888-B2 Vaporizable alkaloid compositions and methods of use thereof SRM, SCLY, SMOX CHRNB4 55/4885CHRNA3 116/4885AADAT 1957/4885
US-12358889-B2 Vaporizable alkaloid compositions and methods of use thereof SRM, SCLY, SMOX CHRNB4 55/4885CHRNA3 116/4885AADAT 1957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.