Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22926878 | 0.89 | TTR (0.47) | ALDH1A1CYP3A4HTR3EHTR3BCYP1A2 | |
| SCHEMBL27200602 | 0.84 | RIPK1 (0.43) | ALDH1A1CYP3A4HTR3EHTR3BCYP1A2 | |
| SCHEMBL27200610 | 0.80 | RIPK1 (0.43) | ALDH1A1CYP3A4HTR3EHTR3BCYP1A2 | |
| SCHEMBL27200606 | 0.77 | TLR8 (0.43) | ALDH1A1CYP3A4HTR3EHTR3BCYP1A2 | |
| SCHEMBL27200595 | 0.77 | ALDH1A1 (0.45) | ALDH1A1CYP3A4HTR3EHTR3BCYP1A2 | |
| SCHEMBL2952239 | 0.76 | TTR (0.46) | ALDH1A1CYP3A4HTR3EHTR3BCYP1A2 | |
| SCHEMBL27200611 | 0.75 | CYP19A1 (0.48) | ALDH1A1CYP3A4HTR3EHTR3BCYP1A2 | |
| SCHEMBL22926873 | 0.75 | KDM4E (0.50) | ALDH1A1CYP3A4SLC6A4HTR3ATTR | |
| SCHEMBL26215055 | 0.74 | RIPK1 (0.45) | ALDH1A1MAPTRIPK1 | |
| SCHEMBL4538021 | 0.73 | CHRNB2 (0.54) | ALDH1A1CYP3A4HTR3EHTR3BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003976-B1 | PICOLINAMIDE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | GLOBACHEM NV (BE) | 2024-04-24 | — | — | EP | disclosed |
| US-20220256855-A1 | PICOLINAMIDE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | GLOBACHEM NV (BE) | 2022-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220256855-A1 | PICOLINAMIDE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | FKBP2, FKBP14, FKBP1A | ALDH1A1 2235/4885CYP3A4 209/4885HTR3E 3674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.