Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1 | Q04771 | 10/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCND3 | P30281 | 1/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26134540 | 0.85 | ALDH1A1 (0.37) | IKBKB | |
| SCHEMBL27206992 | 0.81 | ADRB1 (0.38) | ACVR1IRAK4ADRB1CDK4 | |
| SCHEMBL27202079 | 0.76 | GABRD (0.42) | ACVR1CHRNB2CHRNA4ADRB1CCNA2 | |
| SCHEMBL31398061 | 0.71 | CHRNB2 (0.51) | ACVR1IKBKBCHRNB2CHRNA4TGFBR1 | |
| Hydrochloric Acid SCHEMBL25237677 | 0.70 | CHRNB2 (0.50) | ACVR1IKBKBCHRNB2CHRNA4TGFBR1 | |
| SCHEMBL27202076 | 0.70 | ALDH1A1 (0.48) | ACVR1IRAK4ADRB1 | |
| SCHEMBL28699019 | 0.70 | ACVR1 (0.44) | ACVR1IKBKBCHRNB2CHRNA4ADRB2 | |
| SCHEMBL31288009 | 0.69 | SIRT3 (0.37) | IKBKBCCNA2CDK2 | |
| SCHEMBL28634616 | 0.69 | SIRT3 (0.37) | IKBKBCCNA2CDK2 | |
| SCHEMBL27207432 | 0.69 | ADRB1 (0.39) | ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | MGMT, MCL1, FANCF | ACVR1 4356/4885IKBKB 1966/4885CHRNB2 3913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.